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IC 87114

Known as: IC-87114, IC87114 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AdenineQuinazolines
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family
BackgroundDysfunctions in the PI3K/mTOR pathway have gained a lot of attention in autism research. This was initially based on… 
2015
2015
Phosphoinositide 3-kinase β, phosphoinositide 3-kinase δ, and phosphoinositide 3-kinase γ mediate the anti-inflammatory effects of magnesium sulfate.
2012
2012
Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.
A sensitive and reliable high-performance liquid chromatography-mass spectrometry (LC-MS/MS) was developed and validated for… 
2011
2011
Phosphatidylinositol 3-Kinase Isoform-Specific Effects in Airway Mesenchymal Cell Function
The phosphatidylinositol 3-kinase (PI3K) signal transduction pathway is implicated in the airway remodeling associated with… 
2010
2010
The PH domain adaptor protein Bam32/DAPP1 functions in mast cells to restrain FcɛRI-induced calcium flux and granule release.
Highly Cited
2008
Highly Cited
2008
Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production.
2007
2007
Dissociation between the translocation and the activation of Akt in fMLP‐stimulated human neutrophils—effect of prostaglandin E2
PGE2 and other cAMP‐elevating agents are known to down‐regulate most functions stimulated by fMLP in human polymorphonuclear… 
2006
2006
The p110delta isoform of PI3K differentially regulates beta1 and beta2 integrin-mediated monocyte adhesion and spreading and modulates diapedesis.
OBJECTIVE Leukocyte diapedesis is misregulated in inflammatory disease and depends on the binding of monocytic LFA-1 and VLA-4 to… 
2005
2005
Essential role for the p 110 δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia
The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway has been shown to be frequently activated in blast cells from patients… 
2004
2004
PI 3-Kinase Upregulation and Involvement in Spontaneous Tone in Arteries From DOCA-Salt Rats Is p 110 the Culprit ?
Increased expression of phosphoinositide 3-kinase (PI3-kinase) mediates elevated tone in the aorta from hypertensive… 
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