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IAPP wt Allele

Known as: DAP, Islet Amyloid Polypeptide (Diabetes-Associated Peptide; Amylin) Gene, Islet Amyloid Polypeptide wt Allele 
Human IAPP wild-type allele is located in the vicinity of 12p12.1 and is approximately 25 kb in length. This allele, which encodes islet amyloid… 
National Institutes of Health

Related topics

Related topics

4 relations
12p12.1ApoptosisIntercellular Communication Processreceptor binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Amylin-Induced Cytotoxicity Is Associated with Activation of Caspase-3 and MAP Kinases
Abstract Nanomolar concentrations of human amylin promote death of RINm5F cells in a time and concentrationdependent manner… 
1997
1997
Coexistence of novel amylin-binding sites with calcitonin receptors in human breast carcinoma MCF-7 cells.
Amylin, calcitonin (CT) and calcitonin gene-related peptide (CGRP) share limited structural homology including amino-terminal… 
1996
1996
Acute effects of the human amylin analog AC137 on basal and insulin-stimulated euglycemic and hypoglycemic fuel metabolism in patients with insulin-dependent diabetes mellitus.
Amylin has been reported to decrease glycogen storage in rodent skeletal muscles and produce insulin resistance in intact rats… 
1995
1995
In vivo central actions of rat amylin
1995
1995
SPECIAL REPORT Regulation of muscle glycogen metabolism by CGRP and amylin: CGRP receptors not involved
The aim of the present study was to determine whether amylin and calcitonin gene‐related peptide (CGRP) act through shared or… 
Review
1994
Review
1994
Amylin regulation of fuel metabolism
The 37‐amino acid amylin, co‐secreted from the pancreatic β cells with insulin in response to nutrient stimuli has actions in a… 
Highly Cited
1993
Highly Cited
1993
Response to intravenous injections of amylin and glucagon in fasted, fed, and hypoglycemic rats.
The actions of intravenous glucagon and amylin, a newly discovered hyperglycemic pancreatic islet hormone, have been compared in… 
1993
1993
Anorectic effects of amylin in rats over the life span
1992
1992
Differential effects of amylin on memory processing using peripheral and central routes of administration
Highly Cited
1990
Highly Cited
1990
Islet amyloid polypeptide (IAPP;amylin) influences the endocrine but not the exocrine rat pancreas.
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