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Hypoxia-activated Prodrug TH-4000

Known as: TH-4000 
A proprietary, hypoxia-activated prodrug with potential antineoplastic activity. Upon administration, the hypoxia-activated prodrug TH-4000 is… Expand
National Institutes of Health

Papers overview

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2015
2015
e13548 Background: TH-4000 is a clinical-stage hypoxia-activated prodrug that releases an irreversible tyrosine kinase inhibitor… Expand
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Review
2015
Review
2015
Clinical data indicate that mutant EGFR NSCLC is often heterozygous (PLoS ONE 2013; 8: e54170; PLoS ONE 2009; 4: e7464) and the… Expand
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