Hyperfibrinolysis

Increased degradation of fibrin, associated with clot instability and bleeding []
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Fibrinolysis is a physiologic process maintaining patency of the microvasculature. Maladaptive overactivation of this… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Hyperfibrinolysis (HF) has been reported to occur in a range of 2% to 34% of trauma patients. Using rapid… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The acute coagulopathy of trauma has been identified as a critical determinant of outcomes. Antifibrinolytic agents… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND We investigated whether hyperfibrinolysis and its severity was associated with outcome of traumatized and… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The aim of this study was to diagnose hyperfibrinolysis (HF) and its pattern using thrombelastometry and to correlate… (More)
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2009
2009
The incidence of hyperfibrinolysis in patients with cirrhosis is still debated. The reasons for this uncertainty probably lie in… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Coagulopathy is present at admission in 25% of trauma patients, is associated with shock and a 5-fold increase in… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Blood loss and uncontrollable bleeding are major factors affecting survival in trauma patients. Because treatment with… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Coagulopathy following major trauma is conventionally attributed to activation and consumption of coagulation factors… (More)
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Highly Cited
1976
Highly Cited
1976
The authors describe studies performed on material aspirated from chronic subdural hematomas. Patients were given 51Cr-labeled… (More)
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