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Hyperfibrinolysis

Increased degradation of fibrin, associated with clot instability and bleeding []
National Institutes of Health

Papers overview

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Review
2016
Review
2016
IntroductionViscoelastic assays have been promoted as an improvement over traditional coagulation tests in the management of… Expand
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Review
2015
Review
2015
Fibrin plays an essential role in hemostasis as both the primary product of the coagulation cascade and the ultimate substrate… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Fibrinolysis is a physiologic process maintaining patency of the microvasculature. Maladaptive overactivation of this… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Hyperfibrinolysis (HF) has been reported to occur in a range of 2% to 34% of trauma patients. Using rapid… Expand
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Highly Cited
2011
Highly Cited
2011
INTRODUCTION Blood transfusion is associated with increased morbidity and mortality. We developed and implemented an algorithm… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND: We investigated whether hyperfibrinolysis and its severity was associated with outcome of traumatized and… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The aim of this study was to diagnose hyperfibrinolysis (HF) and its pattern using thrombelastometry and to correlate… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Coagulopathy is present at admission in 25% of trauma patients, is associated with shock and a 5-fold increase in… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Blood loss and uncontrollable bleeding are major factors affecting survival in trauma patients. Because treatment with… Expand
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Highly Cited
2007
Highly Cited
2007
Objectives:Coagulopathy following major trauma is conventionally attributed to activation and consumption of coagulation factors… Expand
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