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Hyperfibrinolysis

Increased degradation of fibrin, associated with clot instability and bleeding []
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Pathogenesis of acute traumatic coagulopathy
Acute traumatic coagulopathy (ATC) is an early endogenous process, driven by the combination of tissue injury and shock that is… 
Highly Cited
2011
Highly Cited
2011
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a…
INTRODUCTION Blood transfusion is associated with increased morbidity and mortality. We developed and implemented an algorithm… 
Highly Cited
2011
Highly Cited
2011
Hyperfibrinolysis Diagnosed by Rotational Thromboelastometry (ROTEM®) Is Associated with Higher Mortality in Patients with Severe Trauma
BACKGROUND: We investigated whether hyperfibrinolysis and its severity was associated with outcome of traumatized and… 
Highly Cited
2010
Highly Cited
2010
Acute coagulopathy of trauma: balancing progressive catecholamine induced endothelial activation and damage by fluid phase anticoagulation.
Review
2009
Review
2009
Resuscitation and transfusion principles for traumatic hemorrhagic shock.
Highly Cited
2008
Highly Cited
2008
Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients.
BACKGROUND Blood loss and uncontrollable bleeding are major factors affecting survival in trauma patients. Because treatment with… 
Review
2008
Review
2008
Hemostasis factors and aging
Review
2003
Review
2003
Pathogenesis and management of the bleeding diathesis in acute promyelocytic leukaemia.
Review
2002
Review
2002
Coagulation disorders in liver disease.
The liver plays a central role in the clotting process, and acute and chronic liver diseases are invariably associated with… 
Review
2001
Review
2001
Aprotinin and the systemic inflammatory response after cardiopulmonary bypass.
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