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Hydrochlorothiazide

Known as: Dihydrochlorothiazide, Dichlothiazide, HCTZ 
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Jonathan L. Halperin, MD, FACC, FAHA, Chair Glenn N. Levine, MD, FACC, FAHA, Chair-Elect Sana M. Al-Khatib, MD, MHS, FACC… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… Expand
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Highly Cited
2008
Highly Cited
2008
There is large interindividual variability in the antiproteinuric response to blockade of the renin-angiotensin-aldosterone… Expand
Highly Cited
2008
Highly Cited
2008
The experimental conditions that affect equilibrium solubility values measured by the classical saturation shake-flask method… Expand
Highly Cited
2006
Highly Cited
2006
Low-dose thiazide-type diuretics are recommended as initial therapy for most hypertensive patients. Chlorthalidone has… Expand
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Review
2004
Review
2004
Review
2004
Thiazide diuretics are one of the preferred pharmacologic treatments for hypertension. Hydrochlorothiazide and chlorthalidone… Expand
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Highly Cited
1999
Highly Cited
1999
ContextThe clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies… Expand
Highly Cited
1989
Highly Cited
1989
It has been suggested that the metabolic side effects of antihypertensive drugs are responsible for their failure to reduce… Expand
Highly Cited
1986
Highly Cited
1986
We conducted a multicenter randomized double-blind clinical trial among 626 men with mild to moderate hypertension to determine… Expand