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Hydrochlorothiazide

Known as: Dihydrochlorothiazide, Dichlothiazide, HCTZ 
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2008
Highly Cited
2008
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… Expand
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Highly Cited
2008
Highly Cited
2008
There is large interindividual variability in the antiproteinuric response to blockade of the renin-angiotensin-aldosterone… Expand
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Highly Cited
2006
Highly Cited
2006
Low-dose thiazide-type diuretics are recommended as initial therapy for most hypertensive patients. Chlorthalidone has… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The efficacy of antihypertensive drugs newer than diuretics and beta-blockers has not been established. We compared… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The efficacy of new antihypertensive drugs has been questioned. We compared the effects of conventional and newer… Expand
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Highly Cited
1999
Highly Cited
1999
ContextThe clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies… Expand
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Highly Cited
1999
Highly Cited
1999
CONTEXT The clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Systolic hypertension increases the risk of dementia in elderly people. The vascular dementia project, set up in the… Expand
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Highly Cited
1989
Highly Cited
1989
It has been suggested that the metabolic side effects of antihypertensive drugs are responsible for their failure to reduce… Expand
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