Hydrochlorothiazide

Known as: Dihydrochlorothiazide, Dichlothiazide, HCTZ 
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This… (More)

Topic mentions per year

Topic mentions per year

1957-2018
010020019572017

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… (More)
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Highly Cited
2006
Highly Cited
2006
Low-dose thiazide-type diuretics are recommended as initial therapy for most hypertensive patients. Chlorthalidone has… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT Despite evidence of efficacy of antihypertensive agents in treating hypertensive patients, safety and efficacy of… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with hypertension and vascular disease, but whether this represents a causal relationship or an… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The efficacy of new antihypertensive drugs has been questioned. We compared the effects of conventional and newer… (More)
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Highly Cited
1997
Highly Cited
1997
Jan A Staessen, Robert Fagard, Lutgarde Thijs, Hilde Celis, Guramy G Arabidze, Willem H Birkenhäger, Christopher J Bulpitt, Peter… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Isolated systolic hypertension occurs in about 15% of people aged 60 years or older. In 1989, the European Working… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Characteristics such as age and race are often cited as determinants of the response of blood pressure to specific… (More)
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Highly Cited
1989
Highly Cited
1989
It has been suggested that the metabolic side effects of antihypertensive drugs are responsible for their failure to reduce… (More)
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Highly Cited
1989
Highly Cited
1989
To detect reasons for the difference in mortality between Scotland and England and Wales a measure of deprivation was studied… (More)
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