FAQ

Human Platelet Antigens

Known as: Antigens, Platelet-Specific, human platelet antigens (HPA), Platelet-Specific Antigens 
Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
0102019552017

Related topics

Related topics

9 relations

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1a alloantigen, human
HPA-1:Type:Pt:Bld:NomHPA-1a:Type:Pt:Bld:NomHPA-3:Type:Pt:Bld:NomIn Blood
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Human Platelet Antigens
physiological aspects
1a alloantigen, human
In Blood
administration & dosage
aspects of radiation effects

Papers overview

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2009
2009
Regulated glycosylation patterns of IgG during alloimmune responses against human platelet antigens.
Various biological activities of immunoglobulin G (IgG) including antibody-dependent cellular cytotoxicity (ADCC) are modulated… (More)
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2006
2006
Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.
OBJECTIVES We studied the modifier effect of platelet antigen polymorphism (PlA2) on platelet inhibition by acetylsalicylic acid… (More)
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Highly Cited
2004
Highly Cited
2004
Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.
Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility genes and quantification of… (More)
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Highly Cited
1998
Highly Cited
1998
The natural history of fetomaternal alloimmunization to the platelet-specific antigen HPA-1a (PlA1, Zwa) as determined by antenatal screening.
Immunization against the human platelet antigen (HPA)-1 alloantigen is the most common cause of severe fetal and neonatal… (More)
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1997
1997
Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not…
BACKGROUND AND PURPOSE A recent study has described a high incidence of the human platelet antigen (HPA)-1b alloantigen in… (More)
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Highly Cited
1996
Highly Cited
1996
Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity.
Patients with both acute and chronic autoimmune thrombocytopenic purpura (AITP) have in vitro lymphocyte defects in the form of… (More)
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1996
1996
Rapid typing for human platelet antigen systems-1, -2, -3 and -5 by PCR amplification with sequence-specific primers.
Typing for human platelet antigens (HPA) is useful in a variety of clinical situations. We developed a method for genotyping for… (More)
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1995
1995
Maternal alloimmunization against fetal platelet antigens: a prospective study.
Neonatal alloimmune thrombocytopenia (NAIT) is induced by maternal alloantibodies to fetal platelet antigens. This prospective… (More)
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1995
1995
Gene frequencies of the five major human platelet antigens in African American, white, and Korean populations.
BACKGROUND The study of the immunogenetics of the human platelet antigens is important to the improvement of diagnosis and… (More)
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1985
1985
Target platelet antigen in homosexual men with immune thrombocytopenia.
A syndrome of isolated immune thrombocytopenic purpura (ITP) has recently been described in homosexual men. We have identified an… (More)
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