Human G(i) Alpha Proteins

Known as: G Protein Alpha Inhibiting Polypeptide, G(i) Alpha Protein, Adenylate Cyclase-Inhibiting G Alpha Protein 
Human G(i) Alpha Proteins (G-Alpha 1 Family) are 40-kDa guanine nucleotide-binding alpha protein subunits of heterotrimeric G protein transducers… (More)
National Institutes of Health

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GNAI1 protein, human
GNAZ proteinGuanine Nucleotide-Binding Protein G(o) Subunit AlphaHeterotrimeric GTP-Binding ProteinsSignal Transduction
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Papers overview

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2012
2012
The ligand specificity of the G-protein-coupled receptor GPR34.
Lyso-PS (lyso-phosphatidylserine) has been shown to activate the G(i/o)-protein-coupled receptor GPR34. Since in vitro and in… (More)
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2011
2011
A novel opioid receptor-mediated enhancement of GABAA receptor function induced by stress in ventral tegmental area neurons.
Opioid receptors are G-protein-coupled receptors (GPCRs) that modulate synaptic function. Depending upon their nervous system… (More)
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2009
2009
Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells.
Low-density lipoprotein (LDL) and lysophosphatidic acid (LPA), one of the lipid components of lipoprotein, induced the DNA… (More)
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2009
2009
Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults.
Stimulation of histamine H(3) receptors (H(3)R) activates G(i/o)-proteins that inhibit adenylyl cyclase and triggers MAPK and… (More)
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2008
2008
ACTIONS OF FINITELY GENERATED GROUPS ON R-TREES
— We study actions of finitely generated groups on R-trees under some stability hypotheses. We prove that either the group splits… (More)
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2003
2003
Extracellular ATP-induced calcium channel inhibition mediated by P1/P2Y purinoceptors in hamster submandibular ganglion neurons.
1. The presence and profile of purinoceptors in neurons of the hamster submandibular ganglion (SMG) have been studied using the… (More)
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2002
2002
μ-Opioid receptor down-regulation and tolerance are not equally dependent upon G-protein signaling
In the present study, the contribution of pertussis toxin (PTX)-sensitive G(i/o)-proteins to opioid tolerance and mu-opioid… (More)
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2001
2001
Role of G(i)-proteins in norepinephrine-mediated vasoconstriction in rat tail artery smooth muscle.
We showed, in rat de-endothelialised tail artery, that pertussis toxin (PTX) (1 microg/mL, 2 hr) attenuated norepinephrine (NE… (More)
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1998
1998
Differential alterations in left and right ventricular G-proteins in congestive heart failure due to myocardial infarction.
In order to examine the status of G-proteins in congestive heart failure due to myocardial infarction, the left coronary artery… (More)
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1997
1997
Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins.
Regulators of G protein signaling (RGS) proteins limit the lifetime of activated (GTP-bound) heterotrimeric G protein a subunits… (More)
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