Skip to search formSkip to main contentSkip to account menu

Hsp90 Inhibitor HSP990

Known as: HSP990 
An orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor Hsp990 binds to and… 
National Institutes of Health

Related topics

Related topics

1 relation
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Retraction: Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig 2-positive glioma tumor-initiating cells.
A University of Texas MD Anderson Cancer Center internal investigation has found that Dr. Jun Fu committed research misconduct as… 
2014
2014
Tumor and Stem Cell Biology TRAP 1 Is Involved in BRAF Regulation and Downstream Attenuation of ERK Phosphorylation and Cell-Cycle Progression : A Novel Target for BRAF-Mutated Colorectal Tumors
Human BRAF-driven tumors are aggressive malignancies with poor clinical outcome and lack of sensitivity to therapies. TRAP1 is a… 
2013
2013
COMBINATIONWITH HYPERTHERMIA AND IRRADIATION ON THE VOLUME OF PANCREATIC CARCINOMA SPHEROIDS
Background: Heat shock protein 90 (Hsp90) is an evolutionary conserved molecular chaperone which participates in protein folding… 
2012
2012
Prostate cancer: Ex vivo efficacy of heat shock protein 90 inhibitors
A study using ex vivo human prostate tumour explants has provided evidence to suggest that heat shock protein 90 (Hsp90) is a… 
2012
2012
Preclinical Development The Novel Oral Hsp 90 Inhibitor NVP-HSP 990 Exhibits Potent and Broad-spectrum Antitumor Activities In Vitro and In Vivo
A novel oral Hsp90 inhibitor, NVP-HSP990, has been developed and characterized in vitro and in vivo. In vitro, NVP-HSP990… 
Review
2011
Review
2011
THE NOVEL ORAL HSP 90 INHIBITOR NVP-HSP 990 EXHIBITS POTENT AND BROAD-SPECTRUM ANTI-TUMOR ACTIVITIES IN VITRO AND IN VIVO
= 176, Text =4987, Figures= 5, Tables= 2, References= 33 on June 23, 2017. © 2012 American Association for Cancer Research. mct… 
2011
2011
IL-6的分泌與肺癌病人存活時間的相關性與抑制IL-6分泌的方法
Interleukin-6 is a pleiotropic cytokine that modulates a variety of physiological functions. It is also associated with many… 
2011
2011
Abstract 2605: Identification and development of NVP-HSP990, a potent and orally active Hsp90 inhibitor for cancer treatment
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)