How Much Distress Weight Loss
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To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal… Expand BACKGROUND
In the 2.8 years of the Diabetes Prevention Program (DPP) randomised clinical trial, diabetes incidence in high-risk… Expand Overweight and obesity affects more than 66% of the adult population and is associated with a variety of chronic diseases. Weight… Expand BACKGROUND
Obesity is associated with increased mortality. Weight loss improves cardiovascular risk factors, but no prospective… Expand Two groups of beneficial bacteria are dominant in the human gut, the Bacteroidetes and the Firmicutes. Here we show that the… Expand CONTEXT
About 5% of the US population is morbidly obese. This disease remains largely refractory to diet and drug therapy, but… Expand Population-based epidemiologic studies have uncovered the high prevalence and wide severity spectrum of undiagnosed obstructive… Expand BACKGROUND
Weight loss causes changes in appetite and energy expenditure that promote weight regain. Ghrelin is a hormone that… Expand Adipocyte complement-related protein (30 kDa) (Acrp30), a secreted protein of unknown function, is exclusively expressed in… Expand BACKGROUND
Leptin, the product of the ob gene, is a hormone secreted by adipocytes. Animals with mutations in the ob gene are… Expand