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Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study.
TLDR
A strong graded relationship is found between the breadth of exposure to abuse or household dysfunction during childhood and multiple risk factors for several of the leading causes of death in adults.
Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study.
TLDR
A strong graded relationship was found between the breadth of exposure to abuse or household dysfunction during childhood and multiple risk factors for several of the leading causes of death in adults.
Excess deaths associated with underweight, overweight, and obesity.
TLDR
Underweight and obesity, particularly higher levels of obesity, were associated with increased mortality relative to the normal weight category and these findings are consistent with the increases in life expectancy in the United States and the declining mortality rates from ischemic heart disease.
Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study.
TLDR
A powerful graded relationship exists between adverse childhood experiences and risk of attempted suicide throughout the life span, and alcoholism, depressed affect, and illicit drug use, which are strongly associated with such experiences, appear to partially mediate this relationship.
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults.
TLDR
The aim of this guideline is to provide useful advice on how to achieve weight reduction and maintenance of a lower body weight and to note that prevention of further weight gain can be a goal for some patients.
The interrelatedness of multiple forms of childhood abuse, neglect, and household dysfunction.
TLDR
The study provides strong evidence that ACEs are interrelated rather than occurring independently, and collecting information about exposure to other ACEs is advisable for studies that focus on the consequences of a specific ACE.
Adverse childhood experiences, alcoholic parents, and later risk of alcoholism and depression.
TLDR
Depression among adult children of alcoholics appears to be largely, if not solely, due to the greater likelihood of having had adverse childhood experiences in a home with alcohol-abusing parents.
Lifetime risk for diabetes mellitus in the United States.
TLDR
For individuals born in the United States in 2000, the lifetime probability of being diagnosed with diabetes mellitus is substantial and primary prevention of diabetes and its complications are important public health priorities.
Adverse childhood experiences and smoking during adolescence and adulthood.
TLDR
Primary prevention of adverse childhood experiences and improved treatment of exposed children could reduce smoking among both adolescents and adults.
Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence
TLDR
This analysis suggests that widespread implementation of reasonably effective preventive interventions focused on high-risk subgroups of the population can considerably reduce, but not eliminate, future increases in diabetes prevalence.
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