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BACKGROUND AND PURPOSE
Elevated plasma homocyst(e)ine may be a causal and modifiable risk factor for ischemic stroke, but the… Expand Cardiovascular disease remains the major cause of morbidity and death in developed countries and accounts for approximately 40… Expand Homocysteine is a sulfur-containing amino acid, rapidly oxidized in plasma to the disulfides homocystine and cysteine… Expand Placental infarction or abruption, recurrent pregnancy loss and pre-eclampsia are thought to arise due to defects within the… Expand BACKGROUND
The Food and Drug Administration (FDA) has recommended that cereal-grain products be fortified with folic acid to… Expand Hyperhomocyst(e)inemia is believed to injure endothelial cells in vivo through a number of mechanisms, including the generation… Expand Studies by various investigators have indicated that elevated levels of plasma homocyst(e)ine are strongly associated with the… Expand BACKGROUND
Plasma levels of homocyst(e)ine are elevated in certain patients with occlusive arterial diseases. We extended these… Expand OBJECTIVE
To assess prospectively the risk of coronary heart disease associated with elevated plasma levels of homocyst(e)ine… Expand The development of atherosclerotic changes and thromboembolism are common features in homocystinurics. Hence, we postulate a… Expand