Holoprosencephaly

Known as: HPEC, HPE, FAMILIAL, Holoprosencephaly (HPE) 
Anterior midline brain, cranial, and facial malformations resulting from the failure of the embryonic prosencephalon to undergo segmentation and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
A confluence of recent breakthroughs in knowledge-aided (KA) processing and adaptive transmit (ATx) radar technologies has… (More)
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Highly Cited
2006
Highly Cited
2006
Holoprosencephaly (HPE), a common defect of human forebrain development, is associated with haploinsufficiency for genes encoding… (More)
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Highly Cited
2003
Highly Cited
2003
Diminished Sonic Hedgehog (Shh) signaling is associated with the most common forebrain defect in humans, holoprosencephaly (HPE… (More)
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Highly Cited
2002
Highly Cited
2002
Holoprosencephaly (HPE) is the most commonly occurring congenital structural forebrain anomaly in humans. HPE is associated with… (More)
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Highly Cited
2000
Highly Cited
2000
The sequencing of the zebrafish genome should be completed by the end of 2002. Direct assignment of function on the basis of this… (More)
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Review
2000
Review
2000
The disease holoprosencephaly is the basis of the most common structural anomaly of the developing forebrain in humans. Numerous… (More)
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Highly Cited
2000
Highly Cited
2000
Holoprosencephaly (HPE) is the most common structural defect of the developing forebrain in humans (1 in 250 conceptuses, 1 in 16… (More)
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Highly Cited
1998
Highly Cited
1998
Holoprosencephaly (HPE) is the most common structural anomaly of the human brain and is one of the anomalies seen in patients… (More)
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Highly Cited
1998
Highly Cited
1998
The steroidal alkaloid cyclopamine produces cyclopia and holoprosencephaly when administered to gastrulation-stage amniote… (More)
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Highly Cited
1977
Highly Cited
1977
One hundred fifty embryos with holoprosencephaly were found among the total of 36,380 conceptuses obtained through induced… (More)
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