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Histatins

Known as: Histatins [Chemical/Ingredient] 
A group of small, histidine-rich, cationic peptides in human SALIVA which are antibacterial and antifungal.
National Institutes of Health

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Dhvar-5P-113D
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2007
2007
Salivary histatins in patients with recurrent oral candidiasis.
The level of salivary histatins was evaluated in 20 patients with a history of recurrent oral candidiasis and in age-, sex… 
Review
2002
Review
2002
Antimicrobial peptides: therapeutic potential for the treatment of Candida infections
The increasing frequency of fungal infections in immunocompromised patients together with the emergence of strains resistant to… 
Highly Cited
2001
Highly Cited
2001
Killing of Candida albicans by Histatin 5: Cellular Uptake and Energy Requirement
Histatins, a group of histidine-rich proteins in human saliva, exhibit antimicrobial activity and are therefore considered to be… 
Highly Cited
2001
Highly Cited
2001
Electron-microscopic demonstration of proline-rich proteins, statherin, and histatins in acquired enamel pellicles in vitro.
Proline-rich proteins (PRPs), histatins, and statherin are salivary proteins that exhibit high affinities for hydroxyapatite… 
Highly Cited
1997
Highly Cited
1997
Inhibition of experimental gingivitis in beagle dogs with topical salivary histatins.
Histatins, histidine-rich proteins found within parotid and submandibular secretions, are a novel class of endogenous peptides… 
Highly Cited
1994
Highly Cited
1994
Physiological Regulation of the Secretion of Histatins and Statherins in Human Parotid Saliva
The small salivary phosphoproteins, histatins and statherins, have important functions in the oral cavity in terms of… 
Highly Cited
1994
Highly Cited
1994
Membrane-induced helical conformation of an active candidacidal fragment of salivary histatins.
1993
1993
Anti-lipopolysaccharide activity of histatins, peptides from human saliva
Histatins are histidine-rich polypeptides secreted in human saliva. They were found to inhibit lipopolysaccharide (LPS)-mediated… 
1990
1990
mRNAs for PRPs, Statherin, and Histatins in von Ebner's Gland Tissues
A search was made for expression of genes for proline-rich proteins (PRPs) and other salivary-type proteins, including statherin… 
Highly Cited
1989
Highly Cited
1989
Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs.
A cDNA coding for histatin 1 was isolated from a human submandibular-gland library and sequenced. This cDNA was used to probe… 
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