Hirschsprung Disease

Known as: disease hirschsprung, MEGACOLON, CONGENITAL, Hirschsprung's Disease 
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
The enteric nervous system (ENS) has been explored by developmental neurobiologists and medical researchers for decades. Whereas… (More)
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Highly Cited
2005
Highly Cited
2005
The identification of common variants that contribute to the genesis of human inherited disorders remains a significant challenge… (More)
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Review
2000
Review
2000
Hirschsprung disease (HSCR), or congenital intestinal aganglionosis, is a relatively common disorder of neural crest migration… (More)
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Highly Cited
1998
Highly Cited
1998
Waardenburg syndrome (WS; deafness with pigmentary abnormalities) and Hirschsprung's disease (HSCR; aganglionic megacolon) are… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE A new endorectal pull-through technique using a transanal approach is presented in this report. METHODS Mucosectomy… (More)
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Highly Cited
1998
Highly Cited
1998
The spontaneous mouse mutant Dominant megacolon (Dom) is a valuable model for the study of human congenital megacolon… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS Subpopulations of interstitial cells of Cajal are regarded as the source of spontaneous slow waves of the gut… (More)
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Highly Cited
1994
Highly Cited
1994
Hirschsprung's disease (HSCR) is characterized by an absence of enteric ganglia in the distal colon and a failure of innervation… (More)
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Highly Cited
1994
Highly Cited
1994
HIRSCHSPRUNG'S disease is a genetic disorder of neural crest development affecting 1 in 5,000 births. It is characterized by the… (More)
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Highly Cited
1990
Highly Cited
1990
Hirschsprung disease, or congenital aganglionic megacolon, is commonly assumed to be a sex-modified multifactorial trait. To test… (More)
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