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Hinge Exons

Known as: Exon, Hinge, Exons, Hinge, Hinge Exon 
Immunoglobulin heavy chain gene exons coding for the hinge region of the heavy chains between the first constant region (on the FAB FRAGMENTS) and… 
National Institutes of Health

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aspects of radiation effectsphysiological aspects

Papers overview

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2016
2016
Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity
ABSTRACT We compared the bactericidal activity of recombinant sets of chimeric IgG monoclonal antibodies against two important… 
2006
2006
A human immunoglobulinIGHG3 allele (Gmb0, b1, c3, c5, u) with anIGHG4 converted region and three hinge exons
The five humanIGHG genes consist of three constant domain exons plus one of or four hinge exon(s), the quadruplicated hinge… 
2003
2003
Characterization of the horse (Equus caballus) IGHA gene
Nucleotide sequences of the immunoglobulin constant heavy chain genes of the horse have been described for IGHM, IGHG and IGHE… 
Highly Cited
1999
Highly Cited
1999
LOSS OF SPLICE CONSENSUS SIGNAL IS RESPONSIBLE FOR THE REMOVAL OF THE ENTIRE CH1 DOMAIN OF THE FUNCTIONAL CAMEL IGG2A HEAVY-CHAIN ANTIBODIES'
1999
1999
Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies.
The molecular basis for the absence of the C(H)1 domain in naturally occurring heavy-chain antibodies of the camelids was… 
Highly Cited
1995
Highly Cited
1995
Structure of abnormal heavy chains in human heavy-chain-deposition disease.
The sequences of two immunoglobulin gamma 1 heavy chains involved in the formation of non-amyloid tissue deposits were determined… 
1988
1988
Gamma heavy chain disease in man. Genomic sequence reveals two noncontiguous deletions in a single gene.
A genomic clone was isolated from a human lymphoid cell line which synthesized an NH2-terminally deleted gamma 3 heavy chain… 
Highly Cited
1982
Highly Cited
1982
Structure of human immunoglobulin gamma genes: implications for evolution of a gene family
Highly Cited
1982
Highly Cited
1982
The nucleotide sequence of a human immunoglobulin C gamma1 gene
We report the nucleotide sequence of a gene encoding the constant region of a human immunoglobulin gamma 1 heavy chain (C gamma 1… 
1981
1981
Amino acid sequence of the first constant region domain and the hinge region of the delta heavy chain of human IgD.
We have determined the amino acid sequence of the first constant (C) region domain (C delta 1) and the hinge region of the delta… 
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