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Heterogeneous-Nuclear Ribonucleoprotein L

Known as: Heterogeneous-Nuclear Ribonucleoprotein L [Chemical/Ingredient], Heterogeneous Nuclear Ribonucleoprotein L, hnRNP L 
A heterogeneous-nuclear ribonucleoprotein found associated with most nascent transcripts, most notably those of the landmark giant loops of amphibian… Expand
National Institutes of Health

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HNRNPL geneIn BloodProcess of secretionagonists
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Papers overview

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2018
2018
The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling
The identification of viability-associated long noncoding RNAs (lncRNAs) might be a promising rationale for new therapeutic… Expand
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2017
2017
Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53
The tumor suppressor p53 is an essential gene in the induction of cell cycle arrest, DNA repair, and apoptosis. p53 protein is… Expand
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Highly Cited
2012
Highly Cited
2012
A Conserved Serine of Heterogeneous Nuclear Ribonucleoprotein L (hnRNP L) Mediates Depolarization-regulated Alternative Splicing of Potassium Channels*
Background: Excitable cells show activity-dependent alternative splicing of ion channels. Results: CaMKIV phosphorylates hnRNP L… Expand
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Highly Cited
2010
Highly Cited
2010
Context-dependent regulatory mechanism of the splicing factor hnRNP L.
Splicing regulatory proteins often have distinct activities when bound to exons versus introns. However, less clear is whether… Expand
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Highly Cited
2007
Highly Cited
2007
Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis.
Alternative mRNA splicing patterns are determined by the combinatorial control of regulator proteins and their target RNA… Expand
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Highly Cited
2007
Highly Cited
2007
Combinatorial Control of Signal-Induced Exon Repression by hnRNP L and PSF
ABSTRACT Cells can regulate their protein repertoire in response to extracellular stimuli via alternative splicing; however, the… Expand
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Highly Cited
2003
Highly Cited
2003
HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats
In the human genome, dinucleotide repeats are common sequence elements of unknown functional significance. Here we demonstrate… Expand
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Highly Cited
1999
Highly Cited
1999
Regulation of Human Vascular Endothelial Growth Factor mRNA Stability in Hypoxia by Heterogeneous Nuclear Ribonucleoprotein L*
A 126-base region of human vascular endothelial growth factor (VEGF) 3′-untranslated region, which we identified as the hypoxia… Expand
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Highly Cited
1998
Highly Cited
1998
Heterogeneous Nuclear Ribonucleoprotein L Interacts with the 3′ Border of the Internal Ribosomal Entry Site of Hepatitis C Virus
ABSTRACT Translation initiation of hepatitis C virus (HCV) RNA occurs by internal entry of a ribosome into the 5′ nontranslated… Expand
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Highly Cited
1995
Highly Cited
1995
HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression.
Most pre-mRNAs require an intron for efficient processing in higher eukaryotes. To test the hypothesis that intron-independent… Expand
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