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Hereditary factor II deficiency disease

Known as: Hereditary Prothrombin Deficiency, Hereditary Factor II Deficiency, DYSPROTHROMBINEMIA 
A very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of prothrombin, resulting in bleeding.
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Prothrombin (factor II [FII]) deficiency is a rare inherited coagulation disorder, having a prevalence of approximately 1 in 2… Expand
Review
2009
Review
2009
Prothrombin deficiency is among the rarest inherited coagulation disorders, with a prevalence of approximately 1:2,000,000. Two… Expand
2001
2001
Several members of a family from Scranton, Pennsylvania were identified to have normal levels of prothrombin antigen while their… Expand
Highly Cited
2000
Highly Cited
2000
Prothrombin deficiency is an autosomal recessive disorder associated with a moderately severe bleeding tendency. In this study… Expand
Review
1998
Review
1998
Prothrombin (factor II) deficiency was first described in 1947 by Quick et al., although the first prothrombin abnormality was… Expand
1998
1998
A 64-year-old white male was referred for evaluation of prolonged prothrombin time (PT) and activated partial thromboplastin time… Expand
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1978
1978
The rarest of reported inherited plasmatic coagulopathies involve prothrombin. Only 10 families with significant reductions of… Expand
1974
1974
Abstract A new congenital dysprothrombinemia is presented. The propositus is a 7-year-old boy who was noted to bleed excessively… Expand
Highly Cited
1969
Highly Cited
1969
A large family has been studied, 11 of whose members have half-normal plasma concentrations of biological prothrombin activity… Expand
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