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Hepatitis C virus genotype 1

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Lower response to simeprevir and sofosbuvir in HCV genotype 1 in routine practice compared with clinical trials
Background High sustained virological response at 12 weeks after end of treatment (SVR12) with 12 weeks of simeprevir and… 
Review
2015
Review
2015
Intracellular accumulation of boceprevir according to plasma concentrations and pharmacogenetics.
2015
2015
Boceprevir early-access for advanced-fibrosis/cirrhosis in Asia-Pacific hepatitis C virus genotype 1 non-responders/relapsers.
AIM To examined the efficacy and safety of treatment with boceprevir, PEGylated-interferon and ribavirin (PR) in hepatitis C… 
2014
2014
IFNL3 (IL28B) and IFNL4 polymorphisms are associated with treatment response in Thai patients infected with HCV genotype 1, but not with genotypes 3 and 6
Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda‐3 (IFNL3 or IL… 
2014
2014
Interleukin‐28B rs12979860 C allele: Protective against advanced fibrosis in chronic hepatitis C genotype 1 infection
While genetic polymorphisms upstream of the interleukin‐28B (IL28B) gene are associated with necroinflammatory activity grade in… 
2013
2013
Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection.
2013
2013
Clinical utility of host genetic IL‐28B variants in hepatitis C virus genotype 1 Asian patients retreated with pegylated interferon plus ribavirin
Host interleukin‐28B (IL‐28B) genetic variants determine a sustained virological response (SVR) in hepatitis C virus genotype 1… 
2013
2013
Impact of Interleukin-28B gene polymorphism (rs12979860) on Egyptian patients infected with hepatitis C virus genotype-4.
Single nucleotide polymorphisms (SNPs) in the Interleukin (IL)-28B gene, namely rs12979860, could predict response to pegylated… 
2012
2012
Host interleukin-28B genetic variants versus viral kinetics in determining responses to standard-of-care for Asians with hepatitis C genotype 1.
2012
2012
IL28B polymorphisms do not predict response to therapy in chronic hepatitis C with HCV genotype 5
We read with interest the paper by Hayes et al 1 on the impact of genetic polymorphisms near IL28B in predicting treatment… 
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