Skip to search formSkip to main contentSkip to account menu

Hemospan

Known as: Hemospan PS 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

maleimide-polyethylene glycol-modified hemoglobin, MP4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
PEGylation promotes hemoglobin tetramer dissociation.
Hemoglobin conjugated with poly(ethylene glycol) (PEG) acts as an oxygen carrier free in plasma, substituting red blood cells in… 
2009
2009
Interference in clinical chemistry assays by the hemoglobin-based oxygen carrier, Hemospan.
2008
2008
Sites of modification of hemospan, a poly(ethylene glycol)-modified human hemoglobin for use as an oxygen therapeutic.
Hemospan is an acellular hemoglobin-based oxygen therapeutic in clinical trials in Europe and the United States. The product is… 
Highly Cited
2008
Highly Cited
2008
CO‐MP4, a polyethylene glycol‐conjugated haemoglobin derivative and carbon monoxide carrier that reduces myocardial infarct size in rats
MP4 (Hemospan) is a Hb‐based oxygen therapeutic agent, based on polyethylene‐glycol (PEG) conjugation to Hb, undergoing clinical… 
Review
2008
Review
2008
Review: Hemoglobin-based blood substitutes increase mortality and myocardial infarction in surgical, trauma, and stroke settings
Question Do hemoglobin-based blood substitutes (HBBSs) increase risk for myocardial infarction (MI) and death more than usual… 
2006
2006
Hemospan: scientific foundations and clinical development
The search for a ‘blood substitute’ is an effort that has been ongoing for over a century, and one that has not fulfilled its… 
Highly Cited
2005
Highly Cited
2005
A phase I single blind clinical trial of a new oxygen transport agent (MP4), human hemoglobin modified with maleimide-activated polyethylene glycol.
BACKGROUND AND OBJECTIVES MP4 (Hemospan), a hemoglobin-based oxygen carrier, has been designed to deliver oxygen to hypoxic… 
2005
2005
A MULTI-CENTER STUDY OF THE SAFETY AND EFFICACY OF MP4 (HEMOSPAN®) IN ORTHOPEDIC SURGERY PATIENTS.: 24
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)