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Hemopexin

Known as: Beta-1B-Glycoprotein, Hemopexin [Chemical/Ingredient], Hemopexins 
Hemopexin (462 aa, ~52 kDa) is encoded by the human HPX gene. This protein plays a role in iron and heme metabolism.
National Institutes of Health

Related topics

Related topics

25 relations

Broader (2)

Binding Proteinsbeta Globulin
Extracellular ProteinExtracellular SpaceGenes, RegulatorHPX gene

Narrower (2)

MMP-9-hemopexinasialohemopexin

Papers overview

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Highly Cited
2015
Highly Cited
2015
Skin mucus proteome of gilthead sea bream: A non-invasive method to screen for welfare indicators.
Highly Cited
2013
Highly Cited
2013
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states
Hemopexin provides neuroprotection in mouse models of stroke and intracerebral hemorrhage and protects neurons in vitro against… 
Highly Cited
2008
Highly Cited
2008
The warm temperature acclimation protein Wap65 as an immune response gene: its duplicates are differentially regulated by temperature and bacterial infections.
2004
2004
The occurrence of two types of hemopexin-like protein in medaka and differences in their affinity to heme
SUMMARY Full-length cDNA clones encoding two types of hemopexin-like protein, mWap65-1 and mWap65-2, were isolated from the HNI… 
2000
2000
Role for copper in transient oxidation and nuclear translocation of MTF-1, but not of NF-kappa B, by the heme-hemopexin transport system.
Heme-hemopexin (2-10 microM) is used as a model for intravenous heme released in trauma, stroke, and ischemia-reperfusion. A… 
1998
1998
Hemopexin from four species inhibits the association of heme with cultured hepatoma cells or primary rat hepatocytes exhibiting a small number of species specific hemopexin receptors
Hemopexin (Hx) binds heme with a very high affinity (Kd<0.1 pmol/L). It has been implicated as a major vehicle for the transport… 
1994
1994
Roles of heme iron-coordinating histidine residues of human hemopexin expressed in baculovirus-infected insect cells.
Hemopexin (Hx), the major heme-binding plasma glycoprotein, scavenges circulating heme and performs an antioxidant function. In… 
Highly Cited
1990
Highly Cited
1990
Hemopexin joins transferrin as representative members of a distinct class of receptor-mediated endocytic transport systems.
Receptor-mediated transport of heme by hemopexin in vivo and in vitro results in catabolism of heme but not the protein… 
Highly Cited
1989
Highly Cited
1989
Receptor-mediated transport of heme by hemopexin regulates gene expression in mammalian cells.
Hemopexin (HPX) transports heme to liver parenchymal cells, undergoes receptor-mediated endocytosis, and recycles intact… 
Highly Cited
1988
Highly Cited
1988
The influence of heme-binding proteins in heme-catalyzed oxidations.
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