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HPX gene

Known as: HEMOPEXIN, HPX, Hemopexin Gene 
This gene plays a role in both heme binding and iron metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Treatment of sickle cell disease (SCD) is hampered by incomplete understanding of pathways linking hemolysis to vaso-occlusion… Expand
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Review
2013
Review
2013
Abstract Research on matrix metalloproteinases (MMPs) and in particular on gelatinase B, alias MMP-9, has grown exponentially in… Expand
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Highly Cited
2010
Highly Cited
2010
Heme from red blood cells released in septic shock worsens organ dysfunction and increases the risk of death, but can be overcome… Expand
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Review
2003
Review
2003
The heme-heme oxygenase system has recently been recognized to possess important regulatory properties. It is tightly involved in… Expand
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Highly Cited
2002
Highly Cited
2002
Membrane-type 1 matrix metalloproteinase (MT1- MMP) localizes at the front of migrating cells and degrades the extracellular… Expand
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Highly Cited
2001
Highly Cited
2001
Activation of proMMP-2 by MT1-MMP is considered to be a critical event in cancer cell invasion. In the activation step, TIMP-2… Expand
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Highly Cited
2000
Highly Cited
2000
Laminin-5 (Ln-5) is an extracellular matrix substrate for cell adhesion and migration, which is found in many epithelial basement… Expand
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Highly Cited
1997
Highly Cited
1997
Soluble proenzyme forms of the catalytic domains of membrane-type matrix metalloproteinases 1 and 2 (MT1-MMP and MT2-MMP) and a… Expand
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Highly Cited
1988
Highly Cited
1988
The pleiotropic effect of the sickle gene suggests that factors in addition to polymerization of the mutant gene product might be… Expand
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Highly Cited
1982
Highly Cited
1982
A human hepatoma cell line, HuH-7, which was established from a hepatocellular carcinoma, was found to replicate continuously in… Expand
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