Heme Oxygenase-1

Known as: Heme Oxygenase-1 [Chemical/Ingredient], Oxygenase-1, Heme, HMOX1 
A ubiquitous stress-responsive enzyme that catalyzes the oxidative cleavage of HEME to yield IRON; CARBON MONOXIDE; and BILIVERDIN.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
020040060019762017

Papers overview

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Highly Cited
2004
Highly Cited
2004
Induction of heme oxygenase-1 (HO-1) is protective in tissue injury in models of allograft rejection and vascular inflammation… (More)
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Highly Cited
2002
Highly Cited
2002
The mechanisms underlying the action of the potent anti-inflammatory interleukin-10 (IL-10) are poorly understood. Here we show… (More)
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Highly Cited
2002
Highly Cited
2002
Heme oxygenase-1 (HO-1) protects cells from various insults including oxidative stress. Transcriptional activators, including the… (More)
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Highly Cited
2001
Highly Cited
2001
Heme oxygenase (HO-1, encoded by Hmox1) is an inducible protein activated in systemic inflammatory conditions by oxidant stress… (More)
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Highly Cited
2000
Highly Cited
2000
Heme oxygenase 1 (HO-1) inhibits apoptosis by regulating cellular prooxidant iron. We now show that there is an additional… (More)
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Highly Cited
1999
Highly Cited
1999
The first known human case of heme oxygenase-1 (HO-1) deficiency is presented in this report. The patient is a six-year-old boy… (More)
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Highly Cited
1999
Highly Cited
1999
Stress response elements, which mediate induction of the mouse heme oxygenase-1 (HO-1) gene by several agents, resemble the… (More)
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Highly Cited
1998
Highly Cited
1998
The rejection of concordant xenografts, such as mouse-to-rat cardiac xenografts, is very similar to the delayed rejection of… (More)
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Highly Cited
1997
Highly Cited
1997
Stressed mammalian cells up-regulate heme oxygenase 1 (Hmox1; EC 1.14.99.3), which catabolizes heme to biliverdin, carbon… (More)
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Highly Cited
1997
Highly Cited
1997
The majority of iron for essential mammalian biological activities such as erythropoiesis is thought to be reutilized from… (More)
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