Haploidentical

Known as: Haploidentical Donor 
A donor who has only one haplotype in common with the recipient.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report
Hematopoietic stem cell transplantation (HSCT) is an established procedure for many acquired and congenital disorders of the… (More)
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Highly Cited
2011
Highly Cited
2011
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation.
Hastening posttransplantation immune reconstitution is a key challenge in human leukocyte antigen (HLA)-haploidentical… (More)
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Highly Cited
2009
Highly Cited
2009
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.
BACKGROUND Procedures to prevent severe graft-versus-host disease (GVHD) delay immune reconstitution secondary to transplants of… (More)
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Highly Cited
2008
Highly Cited
2008
HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide.
We evaluated the safety and efficacy of high-dose, posttransplantation cyclophosphamide (Cy) to prevent graft rejection and graft… (More)
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Highly Cited
2008
Highly Cited
2008
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
BACKGROUND Severe graft-versus-host disease (GVHD) is a life-threatening complication after allogeneic transplantation with… (More)
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Highly Cited
2007
Highly Cited
2007
Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.
We analyzed 112 patients with high-risk acute myeloid leukemia (61 in complete remission [CR]; 51 in relapse), who received human… (More)
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Highly Cited
2007
Highly Cited
2007
Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation.
Haploidentical hematopoietic stem-cell transplantation (HSCT) is associated with an increased risk of graft failure. Adult bone… (More)
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Highly Cited
2005
Highly Cited
2005
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer.
We previously demonstrated that autologous natural killer (NK)-cell therapy after hematopoietic cell transplantation (HCT) is… (More)
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Highly Cited
2005
Highly Cited
2005
Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation.
Aspergillus and cytomegalovirus are major causes of morbidity/mortality after haploidentical hematopoietic transplantation. The… (More)
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Highly Cited
2004
Highly Cited
2004
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
Adult bone-marrow-derived mesenchymal stem cells are immunosuppressive and prolong the rejection of mismatched skin grafts in… (More)
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