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HYOU1 wt Allele

Known as: Hypoxia Up-Regulated 1 wt Allele, ORP150 
Human HYOU1 wild-type allele is located within 11q23.1-q23.3 and is approximately 13 kb in length. This allele, which encodes 150 kDa oxygen… 
National Institutes of Health

Related topics

Related topics

9 relations
11q23.1-q23.3150 kDa oxygen-regulated proteinBreast CarcinomaCell Survival

Broader (1)

HYOU1 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.
Highly Cited
2009
Highly Cited
2009
Oxidized Low-Density Lipoproteins Trigger Endoplasmic Reticulum Stress in Vascular Cells: Prevention by Oxygen-Regulated Protein 150 Expression
Oxidized low-density lipoproteins (oxLDLs) trigger various biological responses potentially involved in atherogenesis. Disturbing… 
Highly Cited
2007
Highly Cited
2007
Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response
Cadmium is a widely distributed nephrotoxic metal that causes renal tubular injury. In this report, we investigated involvement… 
Highly Cited
2007
Highly Cited
2007
Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes
Osteocytes are derived from osteoblasts, but reside in the mineralized bone matrix under hypoxic conditions. Osteocyte-like cells… 
Highly Cited
2001
Highly Cited
2001
Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone.
Expression of angiogenic factors such as vascular endothelial growth factor (VEGF) under conditions of cell stress involves both… 
Highly Cited
2001
Highly Cited
2001
ORP150 protects against hypoxia/ischemia-induced neuronal death
Oxygen-regulated protein 150 kD (ORP150) is a novel endoplasmic-reticulum–associated chaperone induced by hypoxia/ischemia… 
Highly Cited
1999
Highly Cited
1999
150-kDa Oxygen-regulated Protein (ORP150) Suppresses Hypoxia-induced Apoptotic Cell Death*
To determine the contribution of 150-kDa oxygen-regulated protein (ORP150) to cellular processes underlying adaptation to hypoxia… 
Highly Cited
1998
Highly Cited
1998
Expression of the 150-kd oxygen-regulated protein in human breast cancer.
Tumor cells subjected to environmental stress, such as oxygen deprivation followed by reoxygenation, redirect biosynthetic… 
Highly Cited
1997
Highly Cited
1997
Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein, ORP150.
We have cloned a cDNA encoding the human 150 kDa oxygen-regulated protein (ORP150) from hypoxia-treated astrocytoma U373 cDNA… 
Highly Cited
1996
Highly Cited
1996
150-kD oxygen-regulated protein is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxia and modified low density…
The 150-kD oxygen-regulated protein (ORP150) was initially characterized based on its selective expression in astrocytes… 
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