HWA 486

Known as: HWA-486 
 

Topic mentions per year

Topic mentions per year

1985-2014
024619852014

Papers overview

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1999
1999
The isoxazole derivative Leflunomide (HWA 486) is a novel immunoregulatory and anti-inflammatory drug. Affinity chromatography… (More)
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1995
1995
Leflunomide [HWA 486 or RS-34821, 5-methyl-N-(4-trifluoromethylphenyl)-4-isoxazole carboximide] is an immunosuppressive agent… (More)
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1993
1993
Leflunomide (HWA 486), an isoxazol derivative, has been shown to be very effective in combating autoimmune diseases and… (More)
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1991
1991
The compound T-44 (l-benzoyl-2(naphth-l-ylamino)-ethene) exerts phlogistic effects in acute inflammatory models of rats and mice… (More)
  • table 1
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Review
1991
Review
1991
Leflunomide has been shown to be very effective in preventing and curing several autoimmune animal diseases. Further, this agent… (More)
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1989
1989
Experimental tubulointerstitial nephritis (TIN), induced in Brown Norway rats, is an autoimmune disorder in which afflicted… (More)
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1988
1988
MRL/lpr mice spontaneously develop a systemic Lupus erythematosus (SLE)-like disease with a wide range of clinical and… (More)
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1987
1987
HWA 486 was investigated for its ability to modify the development of adjuvant-induced polyarthritis in Lewis rats. HWA 486 (20… (More)
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1986
1986
The novel isoxazol derivative HWA 486 has been shown to prevent the onset of adjuvant disease in Lewis rats [1]. In those studies… (More)
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1985
1985
The new isoxazol derivative, N-(4-Trifluoro-methylphenyl)-5-methylisoxazol-4-carboxamide (HWA 486) has been investigated as to… (More)
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