HUWE1 gene

Known as: KIAA0312, UPSTREAM REGULATORY ELEMENT-BINDING PROTEIN 1, HECT, UBA, AND WWE DOMAINS-CONTAINING PROTEIN 1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2018
051020052018

Papers overview

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2016
2016
Defects in DNA replication, DNA damage response, and DNA repair compromise genomic stability and promote cancer development. In… (More)
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2016
2016
In eukaryotes, many proteins function in multi-subunit complexes that require proper assembly. To maintain complex stoichiometry… (More)
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2015
2015
The E3 ubiquitin ligase HUWE1, deregulated in carcinoma, has been implicated in tumor formation. Here, we uncover a role for… (More)
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2014
2014
Deregulated expression of MYC is a driver of colorectal carcinogenesis, necessitating novel strategies to inhibit MYC function… (More)
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2013
2013
Tumorigenesis results from dysregulation of oncogenes and tumor suppressors that influence cellular proliferation… (More)
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2013
2013
In the intrinsic pathway of apoptosis, cell-damaging signals promote the release of cytochrome c from mitochondria, triggering… (More)
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2012
2012
MyoD is a tissue-specific transcriptional activator that acts as a master switch for muscle development. It activates a broad… (More)
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2012
2012
We previously reported on nonrecurrent overlapping duplications at Xp11.22 in individuals with nonsyndromic intellectual… (More)
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Highly Cited
2008
Highly Cited
2008
Submicroscopic copy-number imbalances contribute significantly to the genetic etiology of human disease. Here, we report a novel… (More)
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2005
2005
A genome wide search for new BH3-containing Bcl-2 family members was conducted using position weight matrices (PWM) and… (More)
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