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HTR6 gene

Known as: SEROTONIN 5-HT-6 RECEPTOR, 5-HT6R, 5-HYDROXYTRYPTAMINE RECEPTOR 6 
National Institutes of Health

Related topics

Related topics

2 relations
HTR1B geneserotonin 6 receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission
2009
2009
Indene-based scaffolds. 2. An indole-indene switch: discovery of novel indenylsulfonamides as 5-HT6 serotonin receptor agonists.
Scaffold selection involving an indole-to-indene core change led to the discovery of a series of indenylsulfonamides that act as… 
2008
2008
5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine
Highly Cited
2007
Highly Cited
2007
Increased Expression of 5-HT6 Receptors in the Rat Dorsomedial Striatum Impairs Instrumental Learning
A number of studies have shown that systemic 5-HT6 receptor antagonists can improve learning and memory, but the mechanism for… 
Highly Cited
2007
Highly Cited
2007
5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus
Highly Cited
2003
Highly Cited
2003
An Assessment of the Effects of Serotonin 6 (5-HT6) Receptor Antagonists in Rodent Models of Learning
Antagonists of serotonin 6 (5-HT6) receptors have been reported to enhance cognition in animal models of learning, although this… 
Review
2000
Review
2000
5-ht6 receptors as emerging targets for drug discovery.
5-ht6 receptors are the latest serotonin receptors to be identified by molecular cloning. Their high affinity for a wide range of… 
Review
1998
Review
1998
Gs Protein‐Coupled Serotonin Receptors: Receptor Isoforms and Functional Differences
ABSTRACT: Three distinct mammalian Gs coupled serotonin receptor genes have been identified, 5‐HT4, 5‐ht6, and 5‐HT7, which… 
Review
1998
Review
1998
The Putative 5‐ht6 Receptor: Localization and Function
ABSTRACT: Until recently, the majority of actions of the neurotransmitter 5‐hydroxytryptamine (5‐HT) were generally believed to… 
1998
1998
Characterization of 5-ht6 receptor and expression of 5-ht6 mRNA in the rat brain during ontogenetic development
We have determined the pharmacological characteristics of the rat 5-ht6 receptor stably expressed in CHO cells. Moreover, using… 
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