HSPPC-96
National Institutes of Health
Papers overview
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Current adjuvant treatment regimens available for the treatment of glioblastoma are widely ineffective and offer a dismal…
2565 Background: HSPPC-96 is derived from a patient's individual tumor and contains glycoprotein-96 (gp96) polypeptide associated…
Introduction: Tumor-derived heat shock protein (HSP)–peptide complexes (HSPPCs) induced immunity against malignancies in…
Heat-shock proteins are highly conserved, stress-induced proteins with chaperone function for trafficking and delivering peptides…
7584 Background: HSPPC-96 (Oncophage; also vitespen) is a novel, autologous, tumor-derived heat shock protein (gp96)-peptide…
The aim of this study was to determine the immunogenicity and antitumor activity of autologous, tumor-derived heat shock protein…
8002 Background: Vitespen (Oncophage; formerly HSPPC-96) is an autologous, tumor-derived, heat shock protein (gp96)-peptide…
7510 Background: We reported that vaccination with melanoma-derived HSPPC-96 resulted in melanoma-specific T-cell response (50…
PURPOSE
Heat shock proteins (HSP) from tumor cells contain the gp96 polypeptide associated with cancer-specific antigenic…
HSPPC-96 is a protein peptide complex consisting of a 96 kDa heat shock protein (Hsp), gp96, and an array of gp96-associated…