gp96 heat shock protein-peptide complex

Known as: Autologous gp96 Heat Shock Protein Peptide Complex Vaccine, gp96 heat shock protein-peptide complex vaccine, gp96 HSP-Peptide Complex 
A vaccine made from a patient's tumor cells that may help the body's immune system kill cancer cells. This vaccine is used to treat kidney cancer, a… (More)
National Institutes of Health

Papers overview

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2012
2012
The structural basis for molecular chaperones to discern misfolded proteins has long been an enigma. As the endoplasmic reticulum… (More)
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Highly Cited
2009
Highly Cited
2009
Extracellular heat shock proteins (HSP) can activate dendritic cells (DC) and monocytes/macrophages, and HSP derived from tumor… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To assess the antitumor activity of vitespen (autologous, tumor- derived heat shock protein gp96 peptide complexes) by… (More)
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2008
2008
Clostridium difficile toxin A (TxA), a key mediator of antibiotic-associated colitis, requires binding to a cell surface receptor… (More)
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Review
2008
Review
2008
Heat shock proteins (HSPs) are a large family of proteins with different molecular weights and different intracellular… (More)
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Highly Cited
2005
Highly Cited
2005
By comparative genomics, we have identified a gene of the intracellular pathogen Listeria monocytogenes that encodes an LPXTG… (More)
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Highly Cited
2004
Highly Cited
2004
Heat shock proteins (HSPs) such as gp96 are released from cells as a result of necrotic cell death. The ability of endogenous HSP… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Heat shock proteins (HSP) from tumor cells contain the gp96 polypeptide associated with cancer-specific antigenic… (More)
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Highly Cited
2000
Highly Cited
2000
Dendritic cells (DC) are key components of innate and adaptive immune responses. The identity of endogenous signals that activate… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Recent evidence has implicated Chlamydia pneumoniae in the aggravation of atherosclerosis. However, the mechanisms by… (More)
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