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gp96 heat shock protein-peptide complex

Known as: Autologous gp96 Heat Shock Protein Peptide Complex Vaccine, gp96 heat shock protein-peptide complex vaccine, gp96 HSP-Peptide Complex 
A vaccine made from a patient's tumor cells that may help the body's immune system kill cancer cells. This vaccine is used to treat kidney cancer, a… 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Background: gp96 is a molecular chaperone that binds and chaperones TLRs and integrins. But the structural basis of such is… 
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Highly Cited
2009
Highly Cited
2009
Extracellular heat shock proteins (HSP) can activate dendritic cells (DC) and monocytes/macrophages, and HSP derived from tumor… 
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Highly Cited
2008
Highly Cited
2008
PURPOSE To assess the antitumor activity of vitespen (autologous, tumor- derived heat shock protein gp96 peptide complexes) by… 
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Review
2008
Review
2008
BACKGROUND Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of… 
Highly Cited
2005
Highly Cited
2005
By comparative genomics, we have identified a gene of the intracellular pathogen Listeria monocytogenes that encodes an LPXTG… 
Highly Cited
2005
Highly Cited
2005
[1] This paper introduces a Maximum Likelihood (ML) approach for estimating the statistical parameters required for the… 
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Highly Cited
2004
Highly Cited
2004
Heat shock proteins (HSPs) such as gp96 are released from cells as a result of necrotic cell death. The ability of endogenous HSP… 
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Highly Cited
2003
Highly Cited
2003
PURPOSE Heat shock proteins (HSP) from tumor cells contain the gp96 polypeptide associated with cancer-specific antigenic… 
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Highly Cited
2000
Highly Cited
2000
Dendritic cells (DC) are key components of innate and adaptive immune responses. The identity of endogenous signals that activate… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Recent evidence has implicated Chlamydia pneumoniae in the aggravation of atherosclerosis. However, the mechanisms by… 
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