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HSD17B6 gene

Known as: 17-BETA-HYDROXYSTEROID DEHYDROGENASE VI, NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase, RODH 
This gene is involved in androgen catabolism.
National Institutes of Health

Related topics

Related topics

6 relations
17-beta-Hydroxysteroid Dehydrogenase Type 6Androgen Metabolism ProcessHSD17B3 geneOxidation-Reduction

Papers overview

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Highly Cited
2012
Highly Cited
2012
Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood
Two unrelated children with HSE carry distinct heterozygous mutations in the gene encoding TANK-binding kinase 1. 
Highly Cited
2011
Highly Cited
2011
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
A new autosomal recessive form of complete TLR3 deficiency reveals that human TLR3 is nonredundant in immunity against herpes… 
Highly Cited
2009
Highly Cited
2009
Heat shock factors HsfB1 and HsfB2b are involved in the regulation of Pdf1.2 expression and pathogen resistance in Arabidopsis.
In order to assess the functional roles of heat stress-induced class B-heat shock factors in Arabidopsis, we investigated T-DNA… 
Highly Cited
2007
Highly Cited
2007
Mechanisms of the anti-hypertensive effect of Hibiscus sabdariffa L. calyces.
Highly Cited
2004
Highly Cited
2004
Synergistic effect of upstream sequences, CCAAT box elements, and HSE sequences for enhanced expression of chimaeric heat shock genes in transgenic tobacco
SummaryThe thermoregulated expression of the soybean heat shock (hs) gene Gmhsp17.3-B is regulated via the heat shock promoter… 
Highly Cited
1996
Highly Cited
1996
Regulation of human heme oxygenase-1 gene expression under thermal stress.
Heme oxygenase-1 is an essential enzyme in heme catabolism, and its human gene promoter contains a putative heat shock element… 
Highly Cited
1993
Highly Cited
1993
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
The endoplasmic reticulum (ER) of eukaryotic cells contains an abundant 78,000-Da protein (BiP) that is involved in the… 
Highly Cited
1993
Highly Cited
1993
Mouse heat shock transcription factors 1 and 2 prefer a trimeric binding site but interact differently with the HSP70 heat shock element
To understand the function of multiple heat shock transcription factors in higher eukaryotes, we have characterized the… 
Highly Cited
1991
Highly Cited
1991
Cooperative binding of drosophila heat shock factor to arrays of a conserved 5 bp unit
Highly Cited
1988
Highly Cited
1988
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.
Activation of human heat shock gene transcription by heat shock, heavy metal ions, and amino acid analogs required the heat shock… 
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