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17-beta-Hydroxysteroid Dehydrogenase Type 6

Known as: Short Chain Dehydrogenase/Reductase Family 9C, Member 6, 3-Alpha->Beta-Hydroxysteroid Epimerase, Hydroxysteroid (17-Beta) Dehydrogenase 6 
17-beta-hydroxysteroid dehydrogenase type 6 (317 aa, ~36 kDa) is encoded by the human HSD17B6 gene. This protein is involved in androgen catabolism.
National Institutes of Health

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Related topics

6 relations
Androgen Metabolism ProcessEnzyme GeneHSD17B6 geneOxidation-Reduction
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2017
2017
Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome
Recently, dihydrotestosterone biosynthesis through the backdoor pathway has been implicated for the human testis in addition to… Expand
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2014
2014
Irreversible sortase A-mediated ligation driven by diketopiperazine formation.
Sortase A (SrtA)-mediated ligation has emerged as an attractive tool in bioorganic chemistry attributing to the remarkable… Expand
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2014
2014
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3) has an essential role in the inactivation of 5α-dihydrotestosterone… Expand
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2006
2006
TEWL measurements as a routine method for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing.
The suitability of transepidermal water loss (TEWL) measurements in vitro as a barrier integrity test for human heat separated… Expand
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2005
2005
Unusual course of herpes simplex virus encephalitis after acyclovir therapy
SummaryThis is a report on a case of herpes simplex encephalitis (HSE) taking an unusual course after initially successful… Expand
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2003
2003
DNA synthesis-dependent and -independent chromatin assembly pathways in Xenopus egg extracts.
Publisher Summary This chapter describes an immunodepletion strategy for Xenopus high-speed egg extracts (HSE) in order to… Expand
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1999
1999
Cloning and characterization of retinol dehydrogenase transcripts expressed in human epidermal keratinocytes.
The normal growth and differentiation of the epidermis require an adequate supply of vitamin A. The active form of vitamin A for… Expand
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1997
1997
Coexpression of the mRNAs encoding retinol dehydrogenase isozymes and cellular retinol-binding protein.
We used in situ hybridization of adult rat tissue to show that mRNAs encoding cellular retinol-binding protein (CRBP) and retinol… Expand
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1995
1995
Cloning of a cDNA for liver microsomal retinol dehydrogenase. A tissue-specific, short-chain alcohol dehydrogenase.
Retinoic acid, a hormone biosynthesized from retinol, controls numerous biological systems by regulating eukaryotic gene… Expand
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1995
1995
Effects of sulfhydryl reagents, retinoids, and solubilization on the activity of microsomal retinol dehydrogenase.
A microsomal retinol dehydrogenase (RoDH) that recognizes holo-cellular retinol binding protein (CRBP) as substrate is inhibited… Expand
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