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HS-173

 
National Institutes of Health

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2019
2019
Necroptosis is a form of regulated necrotic cell death mediated by receptor-interacting kinase 3 (RIP3). Recently, necroptosis… Expand
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2017
2017
Tumor vessels are leaky and immature, which causes poor oxygen and nutrient supply to tumor vessels and results in cancer cell… Expand
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2017
2017
Activation of PI3K/AKT pathway occurs frequently in tumors and is correlated with radioresistance. The PI3K/AKT pathway can be an… Expand
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2017
2017
Graphical abstract Figure. No Caption available. ABSTRACT Multidrug resistance protein 1 (MRP1/ABCC1), an integral transmembrane… Expand
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2017
2017
  • Y. Fan, W. Li, +7 authors H. Ding
  • European journal of medicinal chemistry
  • 2017
  • Corpus ID: 24806414
Phosphatidylinositol 3-kinase (PI3K) is a pivotal regulator of intracellular signaling pathways and considered as a promising… Expand
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2016
2016
Pancreatic cancer is one of the most aggressive solid malignancies prone to metastasis. Epithelial-mesenchymal transition (EMT… Expand
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2013
2013
Hepatic stellate cells (HSCs) are the primary source of matrix components in liver disease such as fibrosis. Phosphatidylinositol… Expand
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2013
2013
We synthesized a novel imidazopyridine analogue, a PI3Kα inhibitor HS-173 and investigated anti-cancer capacity in human cancer… Expand
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2013
2013
The RAF/MEK/ERK and PI3K/AKT pathways are highly implicated in the development of pancreatic cancer. The principal objective of… Expand
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2013
2013
Lung cancer is the leading cause of cancer-related mortality in the world, and non-small cell lung cancer (NSCLC) accounts for… Expand
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