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HPN wt Allele
Known as:
Hepsin wt Allele
, TMPRSS1
, Transmembrane Protease, Serine 1 Gene
Human HPN wild-type allele is located within 19q11-q13.2 and is approximately 26 kb in length. This allele, which encodes serine protease hepsin…
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National Institutes of Health
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Related topics
Related topics
6 relations
Cell Growth Regulation
Hydrolysis
Inhibition of Cell Proliferation
Negative Regulation of Apoptosis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival
Mikko Pelkonen
,
Kaisa Luostari
,
+6 authors
A. Mannermaa
BMC Cancer
2015
Corpus ID: 4695031
BackgroundHepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in…
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Review
2014
Review
2014
Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers
J. Dorn
,
N. Beaufort
,
M. Schmitt
,
E. Diamandis
,
P. Goettig
,
V. Magdolen
Critical reviews in clinical laboratory sciences
2014
Corpus ID: 25698510
Abstract Gynecological cancers, including malignant tumors of the ovaries, the endometrium and the cervix, account for…
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2010
2010
Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
Syazana Hanifa
,
H. Scott
,
P. Crewther
,
M. Guipponi
,
Justin Tan
Neuroreport
2010
Corpus ID: 12662276
Complete deficiency of a member of the type II transmembrane serine protease family, tmprss1 (also known as hepsin), is…
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Highly Cited
2008
Highly Cited
2008
An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss
M. Guipponi
,
Min-Yen Toh
,
+16 authors
H. Scott
Human mutation
2008
Corpus ID: 5636854
Building on our discovery that mutations in the transmembrane serine protease, TMPRSS3, cause nonsyndromic deafness, we have…
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Highly Cited
2007
Highly Cited
2007
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.
M. Guipponi
,
Justin Tan
,
+6 authors
H. Scott
The American journal of pathology
2007
Corpus ID: 13360494
Defective proteolysis has been implicated in hearing loss through the discovery of mutations causing autosomal recessive…
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