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HPN wt Allele

Known as: Hepsin wt Allele, TMPRSS1, Transmembrane Protease, Serine 1 Gene 
Human HPN wild-type allele is located within 19q11-q13.2 and is approximately 26 kb in length. This allele, which encodes serine protease hepsin… 
National Institutes of Health

Related topics

Related topics

6 relations
Cell Growth RegulationHydrolysisInhibition of Cell ProliferationNegative Regulation of Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival
BackgroundHepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in… 
Review
2014
Review
2014
Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers
Abstract Gynecological cancers, including malignant tumors of the ovaries, the endometrium and the cervix, account for… 
2010
2010
Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
Complete deficiency of a member of the type II transmembrane serine protease family, tmprss1 (also known as hepsin), is… 
Highly Cited
2008
Highly Cited
2008
An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss
Building on our discovery that mutations in the transmembrane serine protease, TMPRSS3, cause nonsyndromic deafness, we have… 
Highly Cited
2007
Highly Cited
2007
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.
Defective proteolysis has been implicated in hearing loss through the discovery of mutations causing autosomal recessive… 
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