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HOXB9 gene

Known as: HOX2E, Homeobox B9 Gene, HOXB9 
This gene is involved in both embryonic development and transcriptional regulation.
National Institutes of Health

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Cell Differentiation processChemotaxisHomo sapiensPattern Formation
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HOXB6 wt Allele

Papers overview

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2016
2016
Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo.
HOXB9 is a homeobox-containing gene that plays a key role in mammary gland development and is associated with breast and other… Expand
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2016
2016
PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6
HOXB9 is a homeobox domain-containing transcription factor, playing an important role in embryonic development and cancer… Expand
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2015
2015
The Role of HOXB9 and miR-196a in Head and Neck Squamous Cell Carcinoma
Background Previous studies have demonstrated that a number of HOX genes, a family of transcription factors with key roles in… Expand
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2012
2012
HOXB9 Expression Promoting Tumor Cell Proliferation and Angiogenesis Is Associated with Clinical Outcomes in Breast Cancer Patients
BackgroundStudies have suggested that HOXB9 expression in breast cancer cells promotes cellular invasiveness, metastatic ability… Expand
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Highly Cited
2009
Highly Cited
2009
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
Metastasis from lung adenocarcinoma can occur swiftly to multiple organs within months of diagnosis. The mechanisms that confer… Expand
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Highly Cited
2009
Highly Cited
2009
HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis
The mechanisms underlying tumoral secretion of signaling molecules into the microenvironment, which modulates tumor cell fate… Expand
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2007
2007
Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.
Many members of the nearly 200-strong homeobox gene family have been implicated in cancer, mostly following ectopic expression… Expand
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Highly Cited
2000
Highly Cited
2000
The Leukemia-associated Protein Btg1 and the p53-regulated Protein Btg2 Interact with the Homeoprotein Hoxb9 and Enhance Its Transcriptional Activation*
BTG1 and BTG2 belong to a family of functionally related genes involved in the control of the cell cycle. As part of an ongoing… Expand
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Highly Cited
2000
Highly Cited
2000
Altered HOX and WNT7A expression in human lung cancer.
HOX genes encode transcription factors that control patterning and cell fates. Alterations in HOX expression have been clearly… Expand
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Highly Cited
1999
Highly Cited
1999
Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.
Although the role of Hox genes in patterning the mammalian body plan has been studied extensively during embryonic and fetal… Expand
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