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HOXA9 wt Allele

Known as: MGC1934, HOXA9, ABD-B 
Human HOXA9 wild-type allele is located within 7p15-p14 and is approximately 7 kb in length. This allele, which encodes homeobox protein Hox-A9… 
National Institutes of Health

Related topics

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11 relations
7p15-p14Biologic DevelopmentCell Differentiation processHOXA9 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Haematopoietic stem and progenitor cells from human pluripotent stem cells
A variety of tissue lineages can be differentiated from pluripotent stem cells by mimicking embryonic development through… 
Highly Cited
2015
Highly Cited
2015
Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons.
Highly Cited
2014
Highly Cited
2014
Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation
Loss-of-function mutations of EZH2, a catalytic component of polycomb repressive complex 2 (PRC2), are observed in ~\n10% of… 
Highly Cited
2012
Highly Cited
2012
Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer.
Highly Cited
2009
Highly Cited
2009
Gfi1 integrates progenitor versus granulocytic transcriptional programming.
In patients with severe congenital neutropenia (SCN) and mice with growth factor independent-1 (Gfi1) loss of function, arrested… 
Highly Cited
2006
Highly Cited
2006
Tumor Suppressor p16INK4A Regulates Polycomb-mediated DNA Hypermethylation in Human Mammary Epithelial Cells*
Alterations in DNA methylation are important in cancer, but the acquisition of these alterations is poorly understood. Using an… 
Highly Cited
2006
Highly Cited
2006
Persistent Transactivation by Meis1 Replaces Hox Function in Myeloid Leukemogenesis Models: Evidence for Co-Occupancy of Meis1-Pbx and Hox-Pbx Complexes on Promoters of Leukemia-Associated Genes
ABSTRACT Homeobox transcription factors Meis1 and Hoxa9 promote hematopoietic progenitor self-renewal and cooperate to cause… 
Highly Cited
2006
Highly Cited
2006
Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN‐1)
Testicular germ cell tumours (TGCTs) are classified into two main histological subgroups: seminomas and non‐seminomas. The latter… 
Highly Cited
2005
Highly Cited
2005
Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.
Meis1 is a homeodomain transcription factor coexpressed with Hoxa9 in most human acute myeloid leukemias (AMLs). In mouse models… 
Highly Cited
2004
Highly Cited
2004
Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia.
Identification of the targets of mixed lineage leukemia (MLL) fusion genes will assist in understanding the biology of MLL fusion… 
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