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HOXA10 protein, human
Known as:
PL1 protein, human
, Homeobox Protein Hox-A10
, HOX1H
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Homeobox protein Hox-A10 (410 aa, ~42 kDa) is encoded by the human HOXA10 gene. This protein plays a role in embryonic pattern formation.
National Institutes of Health
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Related topics
Related topics
12 relations
Cell Nucleus
DNA-Binding Proteins
Endometrium
Genes, Regulator
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10
Ya-ting Chen
,
Jin Zhang
,
+8 authors
Duan Ma
BMC Cancer
2012
Corpus ID: 11436474
BackgroundmiRNAs are a group of small RNA molecules regulating target genes by inducing mRNA degradation or translational…
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Highly Cited
2009
Highly Cited
2009
Experimental Murine Endometriosis Induces DNA Methylation and Altered Gene Expression in Eutopic Endometrium1
B. Lee
,
Hongling Du
,
H. Taylor
Biology of Reproduction
2009
Corpus ID: 205354772
Abstract The eutopic endometrium in women with endometriosis demonstrates diminished endometrial receptivity and altered gene…
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Highly Cited
2006
Highly Cited
2006
Deregulation of the HOXA10 homeobox gene in endometrial carcinoma: role in epithelial-mesenchymal transition.
H. Yoshida
,
R. Broaddus
,
Wenjun Cheng
,
S. Xie
,
H. Naora
Cancer Research
2006
Corpus ID: 2159522
Homeobox genes encode transcription factors that control cell differentiation and play essential roles in developmental…
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Highly Cited
2005
Highly Cited
2005
Hox genes specify vertebral types in the presomitic mesoderm.
Marta Carapuço
,
A. Nóvoa
,
N. Bobola
,
M. Mallo
Genes & Development
2005
Corpus ID: 14119198
We show here that expression of Hoxa10 in the presomitic mesoderm is sufficient to confer a Hox group 10 patterning program to…
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Highly Cited
2005
Highly Cited
2005
Activation of Stem‐Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34+ Human Cord Blood Cells
C. Ferrell
,
Sheri T. Dorsam
,
+5 authors
H. Lawrence
Stem Cells
2005
Corpus ID: 6576422
There is growing evidence for a role of HOX homeodomain proteins in normal hematopoiesis. Several HOX genes, including HOXA9 and…
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Highly Cited
2003
Highly Cited
2003
Transcriptional Repression of Peri-Implantation EMX2 Expression in Mammalian Reproduction by HOXA10
Patrick J. Troy
,
G. Daftary
,
C. Bagot
,
H. Taylor
Molecular and Cellular Biology
2003
Corpus ID: 22630069
ABSTRACT HOXA10 is necessary for mammalian reproduction; however, its transcriptional targets are not completely defined. EMX2, a…
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Highly Cited
2002
Highly Cited
2002
Direct regulation of beta3-integrin subunit gene expression by HOXA10 in endometrial cells.
G. Daftary
,
Patrick J. Troy
,
C. Bagot
,
S. Young
,
H. Taylor
Molecular Endocrinology
2002
Corpus ID: 25115309
Estrogen and progesterone regulate HOXA10 expression in the endometrium, where HOXA10 is necessary for implantation. The…
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Highly Cited
2001
Highly Cited
2001
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo.
C. Buske
,
Michaela Feuring-Buske
,
+4 authors
R. Humphries
Blood
2001
Corpus ID: 17715053
Several studies point to multiple members of the Hox transcription factor family as playing key roles in normal hematopoietic…
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Highly Cited
2001
Highly Cited
2001
Maternal Hoxa10 is required for pinopod formation in the development of mouse uterine receptivity to embryo implantation
Catherine N. Bagot
,
H. Kliman
,
Hugh S Taylor
Developmental Dynamics
2001
Corpus ID: 32949161
Hoxa10 is a homeobox gene that is expressed both during the embryogenesis of the genitourinary tract and in the adult…
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Highly Cited
2000
Highly Cited
2000
p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells.
V. Bromleigh
,
Leonard P. Freedman
Genes & Development
2000
Corpus ID: 45041903
The myeolomonocytic cell line U937 differentiates into macrophages in response to a variety of agents. Several genes including…
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