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HMPL-013

Known as: VEGFR-1/2/3 Inhibitor HMPL-013 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
ABSTRACT Introduction: Anti-angiogenetic agents are currently the most commonly used drugs for the treatment of colorectal cancer… 
2017
2017
PurposeFruquintinib (HMPL-013) is a novel, potent, and highly selective tyrosine kinase inhibitor targeting the vascular… 
2016
2016
PurposeFruquintinib (HMPL-013) is a novel oral small molecule compound that selectively inhibits vascular endothelial growth… 
2014
2014
AbstractPurpose This study evaluated the preclinical pharmacokinetics (PK) and disposition of Fruquintinib (HMPL-013), a small… 
2014
2014
VEGF/VEGFR signal axis has been proven to be an important target for development of novel cancer therapies. One challenging…