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HMCN1 gene

Known as: FIBL6, FIBULIN 6, hemicentin 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Planarian EGF repeat-containing genes megf6 and hemicentin are required to restrict the stem cell compartment
The extracellular matrix (ECM) is important for maintaining the boundaries between tissues. This role is particularly critical in… 
2019
2019
SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma.
Cancer‑associated fibroblasts (CAFs) are known to be essential in cancer initiation and development. However, the role of CAFs in… 
Highly Cited
2014
Highly Cited
2014
B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes.
2013
2013
Specific structure and unique function define the hemicentin
Hemicentin has come a long way from when it was first identified in C. elegans as him-4 (High incidence of males). The protein is… 
2010
2010
Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.
BACKGROUND AND OBJECTIVES Diabetic nephropathy (DN) is a multifactorial complication characterized by persistent proteinuria in… 
2010
2010
Variations in TIMP3 are associated with age-related macular degeneration
Extracellular matrix (ECM) remodeling and degradation have been associated with atrophic changes in the retinal pigment… 
Review
2006
Review
2006
Hemicentins: What have we learned from worms?
Hemicentins are conserved extracellular matrix proteins discovered in Caenorhabditis elegans, with orthologs in all vertebrate… 
Highly Cited
2005
Highly Cited
2005
Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent manner
Fibulins are a family of extracellular glycoproteins associated with basement membranes and elastic fibers in vertebrates… 
2004
2004
A novel diagnostic test detects a low frequency of the hemicentin Gln5345Arg variant among Northern Irish age related macular degeneration patients.
PURPOSE Age related macular degeneration (AMD) is a common cause of severe vision loss. Identification of genes involved in AMD… 
Highly Cited
2001
Highly Cited
2001
Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions.
him-4 mutations cause a novel syndrome of tissue fragility, defective cell migration and chromosome instability in Caenorhabditis… 
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