Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

HMCN1 gene

Known as: FIBL6, FIBULIN 6, hemicentin 1 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes.
Basement membrane (BM), a sheet-like form of extracellular matrix, surrounds most tissues. During organogenesis, specific… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
2012
2012
Specific structure and unique function define the hemicentin
Hemicentin has come a long way from when it was first identified in C. elegans as him-4 (High incidence of males). The protein is… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
2010
2010
Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.
BACKGROUND AND OBJECTIVES Diabetic nephropathy (DN) is a multifactorial complication characterized by persistent proteinuria in… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
2007
2007
Case–control genetic association study of fibulin‐6 (FBLN6 or HMCN1) variants in age‐related macular degeneration (AMD)
This article reports a well‐powered age‐related macular degeneration (AMD) case–control association study in the HMCN1 gene… Expand
2006
2006
Hemicentin Assembly in the Extracellular Matrix Is Mediated by Distinct Structural Modules*
Hemicentins are conserved extracellular matrix proteins characterized by a single von Willebrand A (VWA) domain at the amino… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2006
Review
2006
Hemicentins: What have we learned from worms?
Hemicentins are conserved extracellular matrix proteins discovered in Caenorhabditis elegans, with orthologs in all vertebrate… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
Highly Cited
2006
Highly Cited
2006
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population.
PURPOSE A strong association of a Tyr402His polymorphism in the complement factor H (CFH) gene and a Met299Val polymorphism in… Expand
2005
2005
Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent manner
Fibulins are a family of extracellular glycoproteins associated with basement membranes and elastic fibers in vertebrates… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
2004
2004
A novel diagnostic test detects a low frequency of the hemicentin Gln5345Arg variant among Northern Irish age related macular degeneration patients.
PURPOSE Age related macular degeneration (AMD) is a common cause of severe vision loss. Identification of genes involved in AMD… Expand
  • table 1
  • table 2
  • figure 3
  • figure 2
Highly Cited
2001
Highly Cited
2001
Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions.
him-4 mutations cause a novel syndrome of tissue fragility, defective cell migration and chromosome instability in Caenorhabditis… Expand
  • table 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE