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HLA-DRB1 antigen

Known as: HLA DRB1, HLA-DRB1 Chains, human histocompatibility complex derived antigens-DRB1 
A subtype of HLA-DRB beta chains that includes over one hundred allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR… 
National Institutes of Health

Related topics

Related topics

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HLA-DRB1 geneHLA-DRB1 wt AlleleIn Bloodaspects of radiation effects

Narrower (1)

HLA-DRB1*01:02 antigen

Papers overview

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Highly Cited
2015
Highly Cited
2015
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which HLA-B*27 is the major genetic risk… 
Highly Cited
2010
Highly Cited
2010
Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis.
Review
2010
Review
2010
The rheumatoid arthritis HLA–DRB1 shared epitope
Purpose of reviewTo update progress made between December 2008 and November 2009 on the role of the rheumatoid arthritis (RA… 
Highly Cited
2008
Highly Cited
2008
HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk
OBJECTIVE—The Type 1 Diabetes Genetics Consortium has collected type 1 diabetic families worldwide for genetic analysis. The… 
Highly Cited
2008
Highly Cited
2008
Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles
Background: Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis (RA… 
Highly Cited
2005
Highly Cited
2005
High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR–SSOP–Luminex method in the Japanese population
We have developed a new high-throughput, high-resolution genotyping method for the detection of alleles at the human leukocyte… 
Highly Cited
2004
Highly Cited
2004
A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis
Antibodies against cyclic citrullinated peptide (CCP) and rheumatoid factors (RFs) have been demonstrated to predate the onset of… 
Highly Cited
2001
Highly Cited
2001
T Cell Activation in Rheumatoid Synovium Is B Cell Dependent1
Rheumatoid arthritis results from a T cell-driven inflammation in the synovial membrane that is frequently associated with the… 
Highly Cited
1997
Highly Cited
1997
HLA Class II Profile: A Weak Determinant of Factor VIII Inhibitor Development in Severe Haemophilia A
Summary The risk of developing factor VIII inhibitor antibodies in haemophilia A may relate both to factor VIII genotype and… 
Highly Cited
1992
Highly Cited
1992
Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis.
Seropositive rheumatoid arthritis is genetically linked to a group of HLA-DRB1 alleles sharing a sequence motif within the third… 
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