HLA-DRB1 antigen

Known as: HLA DRB1, HLA-DRB1 Chains, human histocompatibility complex derived antigens-DRB1 
A subtype of HLA-DRB beta chains that includes over one hundred allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Rheumatoid arthritis (RA) is strongly associated with the human leukocyte antigen (HLA)-DRB1 locus that possesses the shared… (More)
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Highly Cited
2012
Highly Cited
2012
The genetic association of the major histocompatibility complex (MHC) to rheumatoid arthritis risk has commonly been attributed… (More)
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Highly Cited
2009
Highly Cited
2009
Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region exerts the single strongest… (More)
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Highly Cited
2007
Highly Cited
2007
A recent high-density linkage screen confirmed that the HLA complex contains the strongest genetic factor for the risk of… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The main genetic risk factor for rheumatoid arthritis (RA), the HLA region, has been known for 25 years. Previous… (More)
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Highly Cited
2005
Highly Cited
2005
We have developed a new high-throughput, high-resolution genotyping method for the detection of alleles at the human leukocyte… (More)
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Highly Cited
2005
Highly Cited
2005
High-resolution human leukocyte antigen (HLA) typing exposes the unique patterns of HLA allele and haplotype frequencies in each… (More)
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Highly Cited
2004
Highly Cited
2004
Antibodies against cyclic citrullinated peptide (CCP) and rheumatoid factors (RFs) have been demonstrated to predate the onset of… (More)
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Highly Cited
2003
Highly Cited
2003
Sarcoidosis is a granulomatous disorder of unknown etiology, associated with an accumulation of CD4+ T cells and a TH1 immune… (More)
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Highly Cited
1992
Highly Cited
1992
OBJECTIVE To explore the role of HLA-DRB1 genes in determining disease severity in rheumatoid arthritis. DESIGN Case series of… (More)
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