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HL-60/MX2

HL-60/MX2 is a mitoxantrone resistant derivative of the HL-60 cell line. HL-60/MX2 is approximately 35 fold less sensitive to mitoxantrone than the… 
National Institutes of Health

Papers overview

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2016
2016
Novel topoisomerase II (Topo II) inhibitors have gained considerable interest for the development of anticancer agents. In this… 
2010
2010
Doxorubicin (Dox) is widely used to treat a variety of tumors. However, resistance to this drug is common, making successful… 
Highly Cited
2007
Highly Cited
2007
Analogs of 1,25-dihydroxyvitamin D3 with a reversed configuration at C-1 or C-24 and E or Z geometry of the double bond at C-22… 
2007
2007
In the search for new derivatives of daunorubicin with high activity and/or the ability to overcome the drug resistance barrier… 
2006
2006
Doxorubicin executes topoisomerase II mediated apoptosis, a process known to result in mitochondrial dysfunction, such as the… 
2003
2003
Cellular effects of novel indolo[2,3-b]quinoline derivatives were studied. These compounds are synthetic analogs of plant… 
2001
2001
Peroxisomicine A(1) (T-514) is a dimeric anthracenone first isolated from the plant Karwinskia humboldtiana. The compound… 
2000
2000
BACKGROUND The simple and quick comet assay can quantitatively detect DNA cleavage in cells. This study aimed to determine… 
1992
1992
Modulation of the expression of P-glycoprotein, a plasma membrane protein associated with multidrug resistance, was examined in…