HIRA gene

Known as: TUP1, DIGEORGE SYNDROME CRITICAL REGION GENE 1, histone cell cycle regulator 
This gene plays a role in heterochromatin formation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
0102019932017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The HIRA chaperone complex, comprised of HIRA, UBN1, and CABIN1, collaborates with histone-binding protein ASF1a to incorporate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Cellular senescence is an irreversible proliferation arrest triggered by short chromosome telomeres, activated oncogenes, and… (More)
Is this relevant?
2007
2007
In many animal species, the sperm DNA is packaged with male germ line--specific chromosomal proteins, including protamines. At… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2006
2006
Human HIRA, ASF1a, ASF1b and CAF-1 are evolutionally conserved histone chaperones that form multiple functionally distinct… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
In senescent cells, specialized domains of transcriptionally silent senescence-associated heterochromatic foci (SAHF), containing… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
In sexually reproducing animals, a crucial step in zygote formation is the decondensation of the fertilizing sperm nucleus into a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Plant shoots are characterized by indeterminate growth resulting from the action of a population of stem cells in the shoot… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Deposition of the major histone H3 (H3.1) is coupled to DNA synthesis during DNA replication and possibly DNA repair, whereas… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2003
2003
The Tup1-Ssn6 corepressor complex in Saccharomyces cerevisiae represses the transcription of a diverse set of genes. Chromatin is… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The mammalian HIRA gene encodes a histone-interacting protein whose homolog in Xenopus laevis is characterized here. In vitro… (More)
Is this relevant?