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HIRA gene

Known as: TUP1, DIGEORGE SYNDROME CRITICAL REGION GENE 1, histone cell cycle regulator 
This gene plays a role in heterochromatin formation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Polycomb repressive complex 2 (PRC2) regulates gene expression during lineage specification through trimethylation of lysine 27… Expand
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Highly Cited
2013
Highly Cited
2013
Significance Studies focused on understanding how transcription factors control gene expression have shown that transcription… Expand
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Highly Cited
2010
Highly Cited
2010
The incorporation of histone H3 variants has been implicated in the epigenetic memory of cellular state. Using genome editing… Expand
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Highly Cited
2005
Highly Cited
2005
In senescent cells, specialized domains of transcriptionally silent senescence-associated heterochromatic foci (SAHF), containing… Expand
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Highly Cited
2005
Highly Cited
2005
Candida albicans is the most common human fungal pathogen and causes significant morbidity and mortality worldwide. Nevertheless… Expand
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Highly Cited
2005
Highly Cited
2005
In sexually reproducing animals, a crucial step in zygote formation is the decondensation of the fertilizing sperm nucleus into a… Expand
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Highly Cited
2004
Highly Cited
2004
Deposition of the major histone H3 (H3.1) is coupled to DNA synthesis during DNA replication and possibly DNA repair, whereas… Expand
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Highly Cited
2002
Highly Cited
2002
The mammalian HIRA gene encodes a histone-interacting protein whose homolog in Xenopus laevis is characterized here. In vitro… Expand
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Highly Cited
2002
Highly Cited
2002
The yeast ATF/CREB repressor Sko1(Acr1) regulates genes that are induced upon hyperosmotic stress by recruiting the Cyc8(Ssn6… Expand
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Highly Cited
1998
Highly Cited
1998
We have developed an activator/repressor expression system for budding yeast in which tetracyclines control in opposite ways the… Expand
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