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HINT1 gene

Known as: PKCI-1, HINT, HINT1 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Axonal neuropathy with neuromyotonia: there is a HINT
Mutations in HINT1 cause a common, autosomal-recessive, axonal Charcot-Marie-Tooth neuropathy, often with neuromyotonia. Peeters… 
Highly Cited
2007
Highly Cited
2007
Objective and subjective hearing aid assessment outcomes.
PURPOSE To determine whether specific sentence recognition assessments were sensitive enough to serve as objective outcome… 
Highly Cited
2007
Highly Cited
2007
RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.
Highly Cited
2005
Highly Cited
2005
Adaptation of the HINT (hearing in noise test) for adult Canadian Francophone populations
The HINT provides an efficient and reliable method of assessing speech intelligibility in quiet and in noise by using an adaptive… 
Highly Cited
2004
Highly Cited
2004
Aberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2'-deoxycytidine.
The identification of genes undergoing genetic or epigenetic alterations and contributing to the development of cancer is… 
Highly Cited
2004
Highly Cited
2004
Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 3. The free energy contribution of structural water molecules in HIV-1 protease complexes.
Structural water molecules within protein active sites are relevant for ligand-protein recognition because they modify the active… 
Review
2004
Review
2004
Free energy of ligand binding to protein: evaluation of the contribution of water molecules by computational methods.
One of the more challenging issues in medicinal chemistry is the computation of the free energy of ligand binding to… 
Review
2000
Review
2000
Hydrophobicity: is LogP(o/w) more than the sum of its parts?
Highly Cited
1991
Highly Cited
1991
HINT: A new method of empirical hydrophobic field calculation for CoMFA
SummaryAn empirical hydrophobic field-like 3D function has been calculated with the program HINT (hydrophobic interactions) and… 
Highly Cited
1991
Highly Cited
1991
Allosteric modifiers of hemoglobin. 2. Crystallographically determined binding sites and hydrophobic binding/interaction analysis of novel hemoglobin oxygen effectors.
The protein-bound conformations of six new allosteric effectors similar to bezafibrate that markedly decrease the oxygen affinity… 
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