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HEY2 gene

Known as: GRL, CHF1, FORMERLY, CARDIOVASCULAR BASIC-LOOP-HELIX FACTOR, FORMERLY 
This gene is involved in both transcriptional regulation and Notch signaling pathways.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A mutations in around 20% of cases. Through a… Expand
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Highly Cited
2012
Highly Cited
2012
Activin receptor-like kinase 1 (ALK1) is an endothelial-specific member of the TGF-β/BMP receptor family that is inactivated in… Expand
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Highly Cited
2008
Highly Cited
2008
Background Recent studies have shown that in the developing embryo, arterial and venous identity is established by genetic… Expand
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Highly Cited
2007
Highly Cited
2007
Adequate response to low oxygen levels (hypoxia) by hypoxia inducible factor (HIF) is essential for normal development and… Expand
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Highly Cited
2007
Highly Cited
2007
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… Expand
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Highly Cited
2005
Highly Cited
2005
Notch signaling is required for multiple aspects of cardiovascular development, including arterial-venous differentiation… Expand
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Highly Cited
2004
Highly Cited
2004
The Delta-Notch signaling pathway plays a central role in the development of most vertebrate organs. The Hey family of bHLH… Expand
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Highly Cited
2001
Highly Cited
2001
Arteries and veins are morphologically, functionally and molecularly very different, but how this distinction is established… Expand
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Highly Cited
2000
Highly Cited
2000
The first artery and vein of the vertebrate embryo assemble in the trunk by migration and coalescence of angioblasts to form… Expand
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Highly Cited
1999
Highly Cited
1999
Members of the Hairy/Enhancer of Split family of basic helix-loop-helix (bHLH) transcription factors are regulated by the Notch… Expand
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