HEY2 gene

Known as: GRL, CHF1, FORMERLY, CARDIOVASCULAR BASIC-LOOP-HELIX FACTOR, FORMERLY 
This gene is involved in both transcriptional regulation and Notch signaling pathways.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
051019452017

Papers overview

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2015
2015
Glioblastoma multiforms (GBMs) are highly vascularized brain tumors containing a subpopulation of multipotent cancer stem cells… (More)
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2008
Highly Cited
2008
BACKGROUND Recent studies have shown that in the developing embryo, arterial and venous identity is established by genetic… (More)
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2007
Highly Cited
2007
Adequate response to low oxygen levels (hypoxia) by hypoxia inducible factor (HIF) is essential for normal development and… (More)
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2005
2005
OBJECTIVE Myocardin is a coactivator of serum response factor (SRF) required for vascular smooth muscle cell (VSMC… (More)
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2005
Highly Cited
2005
Notch signaling is required for multiple aspects of cardiovascular development, including arterial-venous differentiation… (More)
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2004
Highly Cited
2004
The Delta-Notch signaling pathway plays a central role in the development of most vertebrate organs. The Hey family of bHLH… (More)
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2002
Highly Cited
2002
Gridlock (grl) is one of the first mutations characterized from the large zebrafish mutagenesis screens, and it results in an… (More)
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2000
Highly Cited
2000
The first artery and vein of the vertebrate embryo assemble in the trunk by migration and coalescence of angioblasts to form… (More)
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2000
Highly Cited
2000
Hey genes (Hey1, Hey2 and HeyL) encode a new group of basic helix-loop-helix transcription factors that are related to the hairy… (More)
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1999
Highly Cited
1999
We have identified a novel subfamily of mammalian hairy/Enhancer of split (E(spl))-related basic helix-loop-helix (bHLH) genes… (More)
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