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HE 3235
Known as:
Androstane Steroid HE3235
, HE-3235
, HE3235
An orally bioavailable adrenal steroid analogue with potential antineoplastic activity. Androstane steroid HE3235 appears to bind the androgen…
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National Institutes of Health
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2012
2012
17α-Alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism
C. Ahlem
,
Michael R. Kennedy
,
+7 authors
J. Frincke
Investigational new drugs
2012
Corpus ID: 24785562
Summary17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235, Apoptone) is an orally bioavailable synthetic analogue of 3…
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2012
2012
Sequencing of Cabazitaxel in Metastatic Castrate-Resistant Prostate Cancer: A Case Report
D. Colbourn
Case Reports in Oncology
2012
Corpus ID: 5719384
Prostate cancer is a common cancer in men; for metastatic disease, it has a 5-year survival rate of 30%. No FDA-approved therapy…
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2011
2011
17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats
C. Ahlem
,
J. Frincke
,
S. White
,
C. Reading
,
R. Trauger
,
R. Lakshmanaswamy
International Journal of Breast Cancer
2011
Corpus ID: 17204097
N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. We explored the antineoplastic…
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