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HDACi 109

National Institutes of Health

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RG2833

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor.
2015
2015
Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere
PurposeLargazole is a potent class I-selective HDACi natural product isolated from the marine cyanobacteria Symploca sp. The… 
2015
2015
The Histone Deacetylase Inhibitor BML-210 Influences Gene and Protein Expression in Human Promyelocytic Leukemia NB4 Cells via Epigenetic Reprogramming
Today, cancer is understood as an epigenetic as well as genetic disease. The main epigenetic hallmarks of the cancer cell are DNA… 
2014
2014
A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo.
2014
2014
Superior antimitogenic and chemosensitization activities of the combination treatment of the histone deacetylase inhibitor apicidin and proteasome inhibitors on human colorectal cancer cells.
Despite the effectiveness of histone deacetylase inhibitors, proteasome inhibitors and cytotoxic drugs on human cancers, none of… 
2013
2013
Radiosensitization by histone deacetylase inhibition in an osteosarcoma mouse model
BackgroundOsteosarcomas (OS) are highly malignant and radioresistant tumors. Histone deacetylase inhibitors (HDACi) constitute a… 
2009
2009
Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells.
2007
2007
p21waf1/Cip1 partially mediates apoptosis in hepatocellular carcinoma cells.
2006
2006
RETRACTED: M344 is a novel synthesized histone deacetylase inhibitor that induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial cancer and ovarian cancer cells
2006
2006
M344 is a novel synthesized histone deacetylase inhibitor that induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial cancer and ovarian cancer cells.
OBJECTIVE Histone deacetylase inhibitors (HDACIs) can inhibit cell proliferation, induce cell cycle arrest, and stimulate… 
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