HDAC4 gene

Known as: KIAA0288, HDACA, HDAC-4 
This gene is involved in chromatin remodeling, repression of gene expression and myoblast differentiation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Epigenetic mechanisms are implicated in gene regulation and the development of different diseases. The epigenome differs between… (More)
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2012
2012
Multiple studies have established that microRNAs (miRNAs) are involved in the initiation and progression of cancer. Notably, miR… (More)
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2011
2011
OBJECTIVE Class IIa histone deacetylases (HDACs) belong to a large family of enzymes involved in protein deacetylation and play a… (More)
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Highly Cited
2010
Highly Cited
2010
Brachydactyly mental retardation syndrome (BDMR) is associated with a deletion involving chromosome 2q37. BDMR presents with a… (More)
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Highly Cited
2008
Highly Cited
2008
The class II Histone deacetylase (HDAC), HDAC4, is expressed in a tissue-specific manner, and it represses differentiation of… (More)
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Highly Cited
2007
Highly Cited
2007
Chondrocyte hypertrophy is essential for endochondral bone development. Unexpectedly, we discovered that MEF2C, a transcription… (More)
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Highly Cited
2006
Highly Cited
2006
Understanding the molecular mechanisms that regulate cellular proliferation and differentiation is a central theme of… (More)
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Highly Cited
2002
Highly Cited
2002
Histone deacetylases (HDACs) play a key role in regulating eukaryotic gene expression. The HDAC domain, homologous to the yeast… (More)
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Highly Cited
2000
Highly Cited
2000
Members of the myocyte enhancer factor-2 (MEF2) family of transcription factors associate with myogenic basic helix–loop–helix… (More)
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Highly Cited
1999
Highly Cited
1999
The acetylation state of histones can influence transcription. Acetylation, carried out by acetyltransferases such as CBP/p300… (More)
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