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HCN1 gene

Known as: HCN1, BCNG1, HAC-2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Hyperexcitability of Mesencephalic Trigeminal Neurons and Reorganization of Ion Channel Expression in a Rett Syndrome Model
People with Rett syndrome (RTT) have defects in motor function also seen in Mecp2‐null mice. Motor function depends on not only… 
2014
2014
TRIP8b Is Required for Maximal Expression of HCN1 in the Mouse Retina
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are cation-selective channels present in retina, brain and… 
2014
2014
Nedd4‐2 regulates surface expression and may affect N‐glycosylation of hyperpolarization‐activated cyclic nucleotide‐gated (HCN)‐1 channels
HCN channels are important regulators of neuronal excitability. The proper function of these channels is governed by various… 
2011
2011
Energetics of Cyclic AMP Binding to HCN Channel C Terminus Reveal Negative Cooperativity*
Cyclic AMP binds to the HCN channel C terminus and variably stabilizes its open state. Using isothermal titration calorimetry, we… 
2009
2009
Selective Hcn1 channels inhibition by ivabradine in mouse rod photoreceptors.
PURPOSE To evaluate in mammalian rod photoreceptors the selectivity for hyperpolarization-activated cyclic nucleotide-gated (Hcn1… 
2008
2008
Novel pharmacological activity of loperamide and CP-339,818 on human HCN channels characterized with an automated electrophysiology assay.
2003
2003
Identification of a Surface Charged Residue in the S3-S4 Linker of the Pacemaker (HCN) Channel That Influences Activation Gating*
I f , encoded by thehyperpolarization-activated cyclicnucleotide-modulated (HCN) channel family, is a key player in cardiac and… 
2003
2003
Hyperpolarization-activated, cyclic AMP-gated, hcn1-like cation channel: the primary, full-length hcn isoform expressed in a saccular hair-cell layer
2003
2003
Helical Secondary Structure of the External S3-S4 Linker of Pacemaker (HCN) Channels Revealed by Site-dependent Perturbations of Activation Phenotype*
If, encoded by the hyperpolarization-activated cyclic nucleotide-modulated channel family (HCN1–4), contributes significantly to… 
2001
2001
Gi- and Gs-coupled receptors up-regulate the cAMP cascade to modulate HCN2, but not HCN1 pacemaker channels
Abstract. A hallmark of native pacemaker channels is their regulation by neurotransmitters and hormones acting through the second… 
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