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HBOC 201

Known as: HBOC-201, hemoglobin glutamer-250, hemoglobin-based oxygen carrier-201 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Blood SubstitutesHemoglobin

Narrower (1)

Hemopure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Traumatic brain injury and severe uncontrolled haemorrhage with short delay pre-hospital resuscitation in a swine model.
Highly Cited
2009
Highly Cited
2009
RESUSCITATION WITH THE HEMOGLOBIN-BASED OXYGEN CARRIER, HBOC-201, IN A SWINE MODEL OF SEVERE UNCONTROLLED HEMORRHAGE AND TRAUMATIC BRAIN INJURY
The purpose of this investigation was to compare the effects of initial resuscitation with HBOC-201 to that of lactated Ringer… 
Highly Cited
2009
Highly Cited
2009
HBOC-201 vasoactivity in a phase III clinical trial in orthopedic surgery subjects--extrapolation of potential risk for acute trauma trials.
BACKGROUND Vasoactivity has hampered progress of hemoglobin-based oxygen carriers (HBOCs) due to concern for adverse blood… 
Review
2008
Review
2008
HBOC-201: the multi-purpose oxygen therapeutic.
Clinical and preclinical studies have revealed a diverse array of indications in which the effectiveness of HBOC-201 has been… 
2006
2006
Prehospital HBOC-201 after traumatic brain injury and hemorrhagic shock in swine.
BACKGROUND Data are limited on the actions of hemoglobin based oxygen carriers (HBOCs) after traumatic brain injury (TBI). This… 
2006
2006
Vasoactivity of bovine polymerized hemoglobin (HBOC-201) in swine with traumatic hemorrhagic shock with and without brain injury.
BACKGROUND We previously reported that bovine polymerized hemoglobin (HBOC- 201) improved outcome in swine with hemorrhagic shock… 
Highly Cited
2004
Highly Cited
2004
A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus Hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation.
BACKGROUND As HBOC-201 improves outcome in animals with hemorrhagic shock (HS), we compared HBOC-201 and HEX (used by U.S… 
2004
2004
Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage.
BACKGROUND Military guidelines call for two 500-mL boluses of Hextend for resuscitation in far-forward environments. This study… 
2003
2003
The pharmacology of tissue oxygenation by biopure's hemoglobin-based oxygen carrier, Hemopure (HBOC-201).
Biopure's hemoglobin-based oxygen carrier, HBOC-201 (Hemopure), enhances oxygen transport by promoting both the convective and… 
1999
1999
Effect of the Hemoglobin-Based Oxygen Carrier HBOC-201 on Laboratory Instrumentation: Cobas Integra, Chiron Blood Gas Analyzer 840, Sysmex™SE-9000 and BCT
Abstract As part of a clinical trial, we evaluated the effects of the hemoglobin-based oxygen-carrier (HBOC) HBOC-201 (an… 
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