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HAVCR1 wt Allele

Known as: KIM1, TIMD1, HAVCR 
Human HAVCR1 wild-type allele is located in the vicinity of 5q33.2 and is approximately 30 kb in length. This allele, which encodes hepatitis A virus… 
National Institutes of Health

Related topics

Related topics

3 relations
5q33.2Immune System ProcessesVirus-Cell Membrane Interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses
Significance Many viruses use phosphatidylserine (PS) receptors to gain entry into target cells, and phagocytes use these… 
Highly Cited
2008
Highly Cited
2008
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice.
T cell Ig mucin (Tim) molecules modulate CD4(+) T cell responses. In keeping with the view that Tim-1 generates a stimulatory… 
Highly Cited
2007
Highly Cited
2007
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.
Members of the T-cell immunoglobulin- and mucin-domain-containing molecule (TIM) family have roles in T-cell-mediated immune… 
Highly Cited
2007
Highly Cited
2007
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
It has been suggested that T cell immunoglobulin mucin (Tim)-1 expressed on T cells serves to positively costimulate T cell… 
Highly Cited
2007
Highly Cited
2007
Human TIM-1 Associates with the TCR Complex and Up-Regulates T Cell Activation Signals
The T cell, Ig domain, and mucin domain-1 (TIM-1) gene is associated with Th2 T cell responses and human atopic diseases. The… 
Highly Cited
2005
Highly Cited
2005
TIM-1 induces T cell activation and inhibits the development of peripheral tolerance
We have examined the function of TIM-1, encoded by a gene identified as an 'atopy susceptibility gene' (Havcr1*), and demonstrate… 
Highly Cited
2005
Highly Cited
2005
T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation.
Polymorphisms in TIM-1, a member of the T cell Ig and mucin (TIM) domain family, are associated with relative susceptibility to… 
Review
2005
Review
2005
The TIM gene family regulates autoimmune and allergic diseases.
Review
2004
Review
2004
TIM-1, a novel allergy and asthma susceptibility gene
Atopic diseases, including asthma, allergic rhinitis, and atopic dermatitis, are caused by environmental factors in genetically… 
Highly Cited
1998
Highly Cited
1998
The Human Homolog of HAVcr-1 Codes for a Hepatitis A Virus Cellular Receptor
ABSTRACT The hepatitis A virus cellular receptor 1 (HAVcr-1) cDNA was isolated from a cDNA expression library of African green… 
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