H19 Imprinted Maternal Untranslated mRNA

Known as: H19, NCRNA00008, Non-Protein Coding RNA 8 
Maternally expressed exclusively and developmentally regulated human putative tumor suppressor H19 Gene encodes H19 Imprinted Maternal Untranslated… (More)
National Institutes of Health

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3 relations
H19 geneH19 wt AlleleHomo sapiens

Papers overview

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Review
2016
Review
2016
Molecular mechanisms of long noncoding RNAs on gastric cancer
Long noncoding RNAs (lncRNAs) are non-protein coding transcripts longer than 200 nucleotides. Aberrant expression of lncRNAs has… (More)
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Highly Cited
2015
Highly Cited
2015
miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction.
Identifying the interaction partners of noncoding RNAs is essential for elucidating their functions. We have developed an… (More)
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Highly Cited
2014
Highly Cited
2014
The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells
The H19 lncRNA has been implicated in development and growth control and is associated with human genetic disorders and cancer… (More)
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Highly Cited
2009
Highly Cited
2009
Exposure of mouse embryos to ethanol during preimplantation development: effect on DNA methylation in the h19 imprinting control region.
In the present study, it was hypothesized that disruption of imprinting control in the H19/Igf2 domain may be a mechanism of… (More)
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Highly Cited
2005
Highly Cited
2005
The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells.
IMP-3, a member of the insulin-like growth factor-II (IGF-II) mRNA-binding protein (IMP) family, is expressed mainly during… (More)
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Highly Cited
2001
Highly Cited
2001
Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer.
The methylation status of binding sites of the insulator protein, CTCF, in the H19 promoter has been suggested as being critical… (More)
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Highly Cited
2000
Highly Cited
2000
Establishment of the paternal methylation imprint of the human H19 and MEST/PEG1 genes during spermatogenesis.
Parental-specific epigenetic modifications are imprinted on a subset of genes in the mammalian genome during germ cell maturation… (More)
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Highly Cited
2000
Highly Cited
2000
H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.
H19 and Igf2 are expressed in a monoallelic fashion from the maternal and paternal chromosomes, respectively. A region upstream… (More)
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Highly Cited
1999
Highly Cited
1999
Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis.
The imprinted mouse H19 gene is hypomethylated on the expressed maternal allele and hypermethylated on the silent paternal allele… (More)
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1993
1993
Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching.
Genomic imprinting and monoallelic gene expression appear to play a role in human genetic disease and tumorigenesis. The human… (More)
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